Pygopus homolog 2 Antibodies

AND PYGO2 ELISA kits, Pygopus homolog 2 Proteins

Many biological assays use antibodies to detect Pygopus homolog 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Pygopus homolog 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Pygopus homolog 2 antibodies...

We validate the specificity of these antibodies to Pygopus homolog 2 by testing them on tissues known to express PYGO2 positively and negatively. Browse below to find the PYGO2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for Pygopus homolog 2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the PYGO2 IHC Guide

PYGO2 Infographic by Boster Bio

All PYGO2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Pygopus 2 Rabbit Monoclonal Antibody

Immunohistochemical analysis of paraffin-embedded human uterus, using Pygopus 2 Antibody

Western blot analysis of Pygopus 2 using anti-Pygopus 2 antibody (M00283)

Human, Mouse

IF, IHC, ICC, WB

$370
Cat # M05260
100 μl

PYGO2 Overview

Facts about Pygopus homolog 2.

PYGO2 3D structure. Source: alphafold

Pygopus homolog 2 (PYGO2)

Involved in signal transduction through the Wnt pathway. .

Gene Information

Human
Gene Name:	PYGO2
Uniprot:	Q9BRQ0
Entrez:	90780

Family

Belongs to:

No superfamily

Alternative Names

1190004M21Rik; FLJ33226; PYGO2; pygopus 2; pygopus homolog 2 (Drosophila); pygopus homolog 2; Pygopus2; Pygopus-2

Molecular Weight

Mass (kDA):
41.244 kDA

Genomic Context


Human

Location:	1q21.3
Sequence:	1; NC_000001.11 (154957026..154961782, complement)

Subcellular Localizations

Nucleus.

Diseases

Malignant Neoplasms
Malignant Paraganglionic Neoplasm
Neoplasms
Carcinoma
Adenoma
Malignant Neoplasm Of Breast
Mammary Neoplasms
Colorectal Cancer
Glioma
Colorectal Neoplasms
Dysostoses
Malignant Neoplasm Of Ovary
Brain Neoplasms

Mandibulofacial Dysostosis
Limb Deformities, Congenital
Limb Defect
Neoplasms, Experimental
Malignant Tumor Of Colon
Infertility
Neoplasms, Glandular And Epithelial

Interacting Proteins

BCL9

Pathways

Cell Cycle
Cell Growth
Cell Proliferation
Histone Modification
Methylation
Reverse Transcription
Chromatin Remodeling
Cell Development
Neurogenesis
Localization
Cell Cycle Arrest
Regeneration
Tissue Development

Histone H3 Acetylation
Telomere Maintenance
S Phase
Histone Acetylation
Histone Methylation
Rna Interference
Kidney Development

PTMs

Acetylation
Methylation

Phosphorylation
Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PYGO2

References

PMID: 11955446 by Kramps T., et al. Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex.