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- Table of Contents
Pnck Antibodies
AND Pnck ELISA kits, Pnck Proteins
Many biological assays use antibodies to detect Pnck, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Pnck in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Pnck antibodies...
Designing an IHC experiment for Pnck? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the PNCK IHC GuidePnck Infographic by Boster Bio
All Pnck Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA
$480
Cat # EKC1856
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1856
1 kit, containing one 96-well plate and all necessary reagents
Pnck Overview
Facts about Calcium/calmodulin-dependent protein kinase type 1B.
Calcium/calmodulin-dependent protein kinase type 1B (Pnck)
Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. In vitro, isoform 1 and isoform 2 phosphorylate CREB1, SYN1/synapsin I.
Phosphorylates and activates CAMK1. .
Gene Information
| Rat | |
|---|---|
| Gene Name: | Pnck |
| Uniprot: | O70150 |
| Entrez: | 29660 |
Family
| Belongs to: |
|---|
| protein kinase superfamily |
Alternative Names
BSTK3; calcium/calmodulin-dependent protein kinase type 1B; CaM kinase I beta; CaM kinase IB; CaMK1b; CaM-KI beta; caMKI-beta; EC 2.7.11; EC 2.7.11.17; FLJ50403; FLJ50549; FLJ56451; FLJ59811; MGC45419; pregnancy up-regulated non-ubiquitously expressed CaM kinase; pregnancy upregulated non-ubiquitously expressed CaM kinase; Pregnancy up-regulated non-ubiquitously-expressed CaM kinase
Molecular Weight
Mass (kDA):
38.439 kDA
Genomic Context
| Rat | |
|---|---|
| Location: | Xq37 |
| Sequence: | X; |
Tissue Specificity
Isoform 1 is expressed in liver, heart, lung, kidney, spleen and testis. Isoform 2 is predominantly expressed in cerebrum and cerebellum.
Diseases
- Nervousness
- Malignant Neoplasms
- Malignant Neoplasm Of Breast
- Cardiac Hypertrophy
- Carcinoma
- Neoplasms
- Globus Hystericus
- Pheochromocytoma
- Hypertrophy
- Carcinogenesis
- Pertussis
- Cell Transformation, Neoplastic
- Hyperplasia
Pathways
- Localization
- Cell Cycle
- Nuclear Export
- Secretion
- Transport
- Protein Phosphorylation
- Osteoclast Differentiation
- Axon Regeneration
- Immune Response
- Muscle Contraction
- Mammary Gland Development
- Translation
- Cell Communication
PTMs
- Phosphorylation
- Dephosphorylation
Research Areas
- Protein Kinase
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Pnck
bosterbio.com/bosterbio-gene-info-cards/Pnck
References
PMID: 9074610 by Yokokura H., et al. Isolation and comparison of rat cDNAs encoding Ca2+/calmodulin- dependent protein kinase I isoforms.
PMID: 9405489 by Naito Y., et al. Isoform-specific activation and structure diversity of calmodulin kinase I.