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- Table of Contents
Peroxiredoxin-1 Antibodies
AND PRDX1 ELISA kits, Peroxiredoxin-1 Proteins
Many biological assays use antibodies to detect Peroxiredoxin-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Peroxiredoxin-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Peroxiredoxin-1 antibodies...
Designing an IHC experiment for Peroxiredoxin-1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the PRDX1 IHC GuidePRDX1 Infographic by Boster Bio
All PRDX1 Products
Product
Figures
Specificity
Applications
Price
Anti-Peroxiredoxin 1/PRDX1 Antibody Picoband®
3 Citations
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # PB9348
100 μg/vial
Cat # PB9348
100 μg/vial
Human, Mouse
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M01845
100 μl
Cat # M01845
100 μl
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M01845-3
20μL, 40μL, 100μL, 200μL
Cat # M01845-3
20μL, 40μL, 100μL, 200μL
Human
$628
Cat # LS005052
20 µg, 100 µg
Cat # LS005052
20 µg, 100 µg
Enzyme Activity, SDS-PAGE
$275
Cat # PROTP35700
Starting from 10ug
Cat # PROTP35700
Starting from 10ug
PRDX1 Overview
Facts about Peroxiredoxin-1.
Peroxiredoxin-1 (PRDX1)
Thiol-specific peroxidase which catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.
Might take part in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2) (PubMed:9497357). Reduces an intramolecular disulfide bond in GDPD5 that gates the capability to GDPD5 to induce postmitotic motor neuron differentiation (By similarity).
Gene Information
| Human | |
|---|---|
| Gene Name: | PRDX1 |
| Uniprot: | Q06830 |
| Entrez: | 5052 |
Family
| Belongs to: |
|---|
| peroxiredoxin family |
Alternative Names
EC 1.11.1; EC 1.11.1.15; Natural killer cell-enhancing factor A; natural killer-enhancing factor A; NKEFA; NKEF-A; PAG; PAGAMSP23; PAGB; Peroxiredoxin 1; peroxiredoxin-1; PRDX1; proliferation-associated gene A; Proliferation-associated gene protein; PRX1; PRXI; TDPX2; Thioredoxin peroxidase 2; Thioredoxin-dependent peroxide reductase 2
Molecular Weight
Mass (kDA):
22.11 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p34.1 |
| Sequence: | 1; NC_000001.11 (45511035..45522890, complement) |
Subcellular Localizations
Cytoplasm. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Lung Neoplasms
- Adenocarcinoma
- Carcinogenesis
- Cell Transformation, Neoplastic
- Malignant Neoplasm Of Lung
- Inflammation
- Diabetes Mellitus
- Malignant Paraganglionic Neoplasm
- Malignant Squamous Cell Neoplasm
- Neoplasm Metastasis
Interacting Proteins
- AR
- PRNP
- PTEN
- SRXN1
- STK4
- TERF1
- TPT1
Pathways
- Cell Death
- Cell Proliferation
- Pathogenesis
- Response To Oxidative Stress
- Localization
- Cell Differentiation
- Cell Cycle
- Translation
- Neuroprotection
- Cell Migration
- Embryo Development
- Oocyte Maturation
- Transport
PTMs
- Oxidation
- Phosphorylation
- Reduction
- Acetylation
Research Areas
- Core ESC-Like Genes
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PRDX1
bosterbio.com/bosterbio-gene-info-cards/PRDX1
References
PMID: 8496166 by Prosperi M.T., et al. A human cDNA corresponding to a gene overexpressed during cell proliferation encodes a product sharing homology with amoebic and bacterial proteins.
PMID: 8026862 by Shau H., et al. Cloning and sequence analysis of candidate human natural killer- enhancing factor genes.
1 Publications of Boster Peroxiredoxin-1 Antibodies & ELISA Kits
- PubMed ID: 10.3389/fnins.2020.00181, Prdx1 Reduces Intracerebral Hemorrhage-Induced Brain Injury via Targeting Inflam...
*More publications can be found for each product on its corresponding product page