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- Table of Contents
RAMP1 Antibodies
AND RAMP1 ELISA kits, RAMP1 Proteins
Many biological assays use antibodies to detect RAMP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RAMP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RAMP1 antibodies...
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RAMP1 Overview
Facts about Receptor activity-modifying protein 1.
Receptor activity-modifying protein 1 (RAMP1)
Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) into the plasma membrane. Acts as a receptor for calcitonin-gene-related peptide (CGRP) together with CALCRL.
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Gene Information
| Human | |
|---|---|
| Gene Name: | RAMP1 |
| Uniprot: | O60894 |
| Entrez: | 10267 |
Family
| Belongs to: |
|---|
| RAMP family |
Alternative Names
calcitonin receptor-like receptor activity modifying protein 1; Calcitonin-receptor-like receptor activity-modifying protein 1; CRLR activity-modifying protein 1; RAMP1; receptor (calcitonin) activity modifying protein 1; receptor (G protein-coupled) activity modifying protein 1; receptor activity modifying protein 1; receptor activity-modifying protein 1
Molecular Weight
Mass (kDA):
16.988 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2q37.3 |
| Sequence: | 2; NC_000002.12 (237858555..237912114) |
Tissue Specificity
Expressed in many tissues including the uterus, bladder, brain, pancreas and gastro-intestinal tract.
Subcellular Localizations
Membrane; Single-pass type I membrane protein.
Diseases
- Migraine Disorders
- Hypertensive Disease
- Pain
- Nervousness
- Headache
- Hypertrophy
- Inflammation
- Hypoxia
- Fibrosis
- Neoplasms
- Anoxia
- Disease Of Adrenal Medulla
Interacting Proteins
- CALCRL
Pathways
- Localization
- Transport
- Secretion
- Vasodilation
- Pathogenesis
- Glycosylation
- Cell Proliferation
- Reverse Transcription
- Angiogenesis
- Receptor Internalization
- Innervation
- Sensitization
- Endocytosis
PTMs
- Glycosylation
- Phosphorylation
- Cleavage
- Amidation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RAMP1
bosterbio.com/bosterbio-gene-info-cards/RAMP1
References
PMID: 9620797 by McLatchie L.M., et al. RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor.
PMID: 18725456 by Kusano S., et al. Crystal structure of the human receptor activity-modifying protein 1 extracellular domain.