RAMP1 Antibodies

AND RAMP1 ELISA kits, RAMP1 Proteins

Many biological assays use antibodies to detect RAMP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RAMP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RAMP1 antibodies...

We validate the specificity of these antibodies to RAMP1 by testing them on tissues known to express RAMP1 positively and negatively. Browse below to find the RAMP1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for RAMP1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the RAMP1 Western Blot Guide

RAMP1 Infographic by Boster Bio

All RAMP1 Products

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Product

Figures

Specificity

Applications

Price

RAMP1 (NM_005855) Human Over-expression Lysate

Human

$628
Cat # LS010267
20 µg, 100 µg

Anti-RAMP1 Antibody

Western blot (WB) analysis of RAMP1 polyclonal antibody at 1:500 dilution
Lane1:Hela whole cell lysate
Lane2:NIH-3T3 whole cell lysate
Lane3:H9C2 whole cell lysate

Human, Mouse, Rat

$405
Cat # A04978
100ul

Human RAMP1 Recombinant Protein

3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain

SDS-PAGE, Denatured

$265
Cat # PROTO60894
Starting from 10ug

RAMP1 Overview

Facts about Receptor activity-modifying protein 1.

RAMP1 3D structure. Source: alphafold

Receptor activity-modifying protein 1 (RAMP1)

Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) into the plasma membrane. Acts as a receptor for calcitonin-gene-related peptide (CGRP) together with CALCRL.

Gene Information

Human
Gene Name:	RAMP1
Uniprot:	O60894
Entrez:	10267

Family

Belongs to:

RAMP family

Alternative Names

calcitonin receptor-like receptor activity modifying protein 1; Calcitonin-receptor-like receptor activity-modifying protein 1; CRLR activity-modifying protein 1; RAMP1; receptor (calcitonin) activity modifying protein 1; receptor (G protein-coupled) activity modifying protein 1; receptor activity modifying protein 1; receptor activity-modifying protein 1

Molecular Weight

Mass (kDA):
16.988 kDA

Genomic Context


Human

Location:	2q37.3
Sequence:	2; NC_000002.12 (237858555..237912114)

Tissue Specificity

Expressed in many tissues including the uterus, bladder, brain, pancreas and gastro-intestinal tract.

Subcellular Localizations

Membrane; Single-pass type I membrane protein.

Diseases

Migraine Disorders
Hypertensive Disease
Pain
Nervousness
Headache
Hypertrophy
Inflammation
Hypoxia
Fibrosis
Neoplasms
Anoxia
Disease Of Adrenal Medulla

Tumor Angiogenesis
Pathologic Vasoconstriction
Chimera Disorder
Pulmonary Hypertension
Pheochromocytoma
Cardiovascular Diseases
Ischemia

Interacting Proteins

CALCRL

Pathways

Localization
Transport
Secretion
Vasodilation
Pathogenesis
Glycosylation
Cell Proliferation
Reverse Transcription
Angiogenesis
Receptor Internalization
Innervation
Sensitization
Endocytosis

Cytokine Production
Bone Resorption
Osteoblast Proliferation
Testosterone Secretion
Diestrus
Cellular Localization
Hypersensitivity

PTMs

Glycosylation
Phosphorylation
Cleavage
Amidation

Nitration
Oxidation
Reduction
Iodination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RAMP1

References

PMID: 9620797 by McLatchie L.M., et al. RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor.

PMID: 18725456 by Kusano S., et al. Crystal structure of the human receptor activity-modifying protein 1 extracellular domain.