RASGEF1B Antibodies

AND RASGEF1B ELISA kits, RASGEF1B Proteins

Many biological assays use antibodies to detect RASGEF1B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RASGEF1B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RASGEF1B antibodies...

We validate the specificity of these antibodies to RASGEF1B by testing them on tissues known to express RASGEF1B positively and negatively. Browse below to find the RASGEF1B antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: Septin9 Next: DAB2IP

RASGEF1B Infographic by Boster Bio

All RASGEF1B Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-RGF1B RASGEF1B Antibody

Human, Mouse

ELISA, WB

$380
Cat # A11320
100ul

RASGEF1B Overview

Facts about Ras-GEF domain-containing family member 1B.

RASGEF1B 3D structure. Source: alphafold

Ras-GEF domain-containing family member 1B (RASGEF1B)

Guanine nucleotide exchange factor (GEF) with specificity for RAP2A, it doesn't seems to trigger other Ras family proteins (in vitro). .

Gene Information

Human
Gene Name:	RASGEF1B
Uniprot:	Q0VAM2
Entrez:	153020

Family

Belongs to:

No superfamily

Alternative Names

RasGEF domain family, member 1B; ras-GEF domain-containing family member 1B

Molecular Weight

Mass (kDA):
55.359 kDA

Genomic Context


Human

Location:	4q21.21
Sequence:	4; NC_000004.12 (81426393..81471907, complement)

Subcellular Localizations

Early endosome. Late endosome. Midbody. May shuttle between early and late endosomes (By similarity). Localizes to midbody at telophase.

Diseases

Muscle Hypotonia
Haploinsufficiency
Growth Disorders
Congenital Anomaly Of Face
Speech Delay
Dwarfism
Brachydactyly
Cytogenetic Abnormality
Cleft Lip
Neuroblastoma
Neurofibroma
Language Development Disorders

Developmental Delay (disorder)
Dystonia Disorders
Cleft Palate
Tissue Adhesions
Epilepsy
Lissencephaly

Pathways

Cell Adhesion
Cell Proliferation
Regulation Of Cell Adhesion
Cell Cycle
Regulation Of Cell Proliferation
S Phase
Cell Differentiation
Immune Response
Endosome Localization

Localization
Epiboly
Cell Maturation

PTMs

Phosphorylation

Research Areas

Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RASGEF1B

References

PMID: 12488504 by Ferreira L.R.P., et al. Identification and characterization of a novel mouse gene encoding a Ras-associated guanine nucleotide exchange factor: expression in macrophages and myocarditis elicited by Trypanosoma cruzi parasites.

PMID: 19645719 by Yaman E., et al. RasGEF1A and RasGEF1B are guanine nucleotide exchange factors that discriminate between Rap GTP-binding proteins and mediate Rap2- specific nucleotide exchange.