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- Table of Contents
Designing an IHC experiment for RERG? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the RERG IHC GuideFacts about Ras-related and estrogen-regulated growth inhibitor.
In cell lines overexpression leads to a decline in the rate of proliferation, colony formation and in tumorigenic potential. .
| Human | |
|---|---|
| Gene Name: | RERG |
| Uniprot: | Q96A58 |
| Entrez: | 85004 |

| Belongs to: |
|---|
| small GTPase superfamily |

MGC15754; RAS-like, estrogen-regulated, growth inhibitor; ras-related and estrogen-regulated growth inhibitor
Mass (kDA):
22.608 kDA

| Human | |
|---|---|
| Location: | 12p12.3 |
| Sequence: | 12; NC_000012.12 (15107783..15221417, complement) |
Detected in heart, brain, placenta, lung, liver, skin, kidney and pancreas. Detected in estrogen receptor- positive breast-derived cell lines, but not in estrogen receptor- negative cell lines. Expression is decreased or lost in a significant proportion of primary breast tumors with poor clinical prognosis.
Cytoplasm.





PMID: 11533059 by Finlin B.S., et al. RERG is a novel ras-related, estrogen-regulated and growth-inhibitory gene in breast cancer.