RGS7 Antibodies

AND RGS7 ELISA kits, RGS7 Proteins

Many biological assays use antibodies to detect RGS7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RGS7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RGS7 antibodies...

We validate the specificity of these antibodies to RGS7 by testing them on tissues known to express RGS7 positively and negatively. Browse below to find the RGS7 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for RGS7? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the RGS7 IHC Guide

RGS7 Infographic by Boster Bio

All RGS7 Products

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Product

Figures

Specificity

Applications

Price

Anti-RGS7 Antibody Picoband®

Western blot analysis of RGS7 using anti-RGS7 antibody (A04305-1)

IF analysis of RGS7 using anti-RGS7 antibody (A04305-1)

Flow Cytometry analysis of 293T cells using anti-RGS7 antibody (A04305-1)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A04305-1
100 μg/vial

Anti-RGS7 Antibody

Immunohistochemical analysis of paraffin-embedded human Gastric adenocarcinoma

Western blot analysis of lysates from Jurkat cells, using RGS7 Antibody

Human, Mouse, Rat

ELISA, IHC, WB

$335
Cat # A04305
100ul

RGS7 (NM_002924) Human Over-expression Lysate

Human

$628
Cat # LS006000
20 µg, 100 µg

RGS7BP (NM_001029875) Human Over-expression Lysate

Human

$628
Cat # LS401190
20 µg, 100 µg

RGS7 (NM_002924) Human Recombinant Protein

Coomassie blue staining of purified RGS7 protein

$1249
Cat # PROTP49802
20 µg

RGS7 Overview

Facts about Regulator of G-protein signaling 7.

RGS7 3D structure. Source: alphafold

Regulator of G-protein signaling 7 (RGS7)

Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:10521509, PubMed:10862767).

The RGS7/GNB5 dimer enhances GNAO1 GTPase activity (PubMed:10521509). May play a role in synaptic vesicle exocytosis (PubMed:12659861).

Gene Information

Human
Gene Name:	RGS7
Uniprot:	P49802
Entrez:	6000

Family

Belongs to:

No superfamily

Alternative Names

regulator of G-protein signaling 7; regulator of G-protein signaling RGS7; regulator of G-protein signalling 7

Molecular Weight

Mass (kDA):
57.668 kDA

Genomic Context


Human

Location:	1q43\|1q23.1
Sequence:	1; NC_000001.11 (240774742..241357230, complement)

Subcellular Localizations

Cytoplasm, cytosol. Cytoplasm. Cell membrane. Membrane; Peripheral membrane protein; Cytoplasmic side. Interaction with PKD1 promotes location at the cell membrane (PubMed:10339594). Interaction with RGS7BP promotes location at the cell membrane (PubMed:15897264).

Diseases

Nervousness
Substance Withdrawal Syndrome
Malignant Neoplasms
Pertussis
Schizophrenia
Polycystic Kidney Diseases
Kidney Diseases
Janiceps
Sclerosis
Adenoma
Brain Ischemia

Spinal Cord Injuries
Pulmonary Embolism
Myelitis
Malignant Tumor Of Colon
Glioma
Physical Dependence

Pathways

Localization
Phototransduction
Brain Development
Proteolysis
Synaptic Transmission
Mating
Chondrocyte Differentiation
Cell Cycle Arrest
Cartilage Development
Cell Division
Response To Morphine
Mismatch Repair
Asymmetric Cell Division

Cytokine Production
Cell Cycle
Synaptic Vesicle Exocytosis
Locomotion
Protein Folding
Exocytosis
Pathogenesis

PTMs

Phosphorylation
Palmitoylation

Depalmitoylation
Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RGS7

References

PMID: 10339594 by Kim E., et al. Interaction between RGS7 and polycystin.

PMID: 8548815 by Koelle M.R., et al. EGL-10 regulates G protein signaling in the C. elegans nervous system and shares a conserved domain with many mammalian proteins.