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- Table of Contents
RRM2 Antibodies
AND RRM2 ELISA kits, RRM2 Proteins
Many biological assays use antibodies to detect RRM2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RRM2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RRM2 antibodies...
Designing an IHC experiment for RRM2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the RRM2 IHC GuideRRM2 Infographic by Boster Bio
All RRM2 Products
Product
Figures
Specificity
Applications
Price
RRM2 Overview
Facts about Ribonucleoside-diphosphate reductase subunit M2.
Ribonucleoside-diphosphate reductase subunit M2 (RRM2)
Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
Inhibits Wnt signaling. .
Gene Information
| Human | |
|---|---|
| Gene Name: | RRM2 |
| Uniprot: | P31350 |
| Entrez: | 6241 |
Family
| Belongs to: |
|---|
| ribonucleoside diphosphate reductase small chain family |
Alternative Names
EC 1.17.4.1; R2; ribonucleoside-diphosphate reductase subunit M2; ribonucleotide reductase M2 polypeptide; ribonucleotide reductase M2; Ribonucleotide reductase small chain; Ribonucleotide reductase small subunit; RR2; RR2M
Molecular Weight
Mass (kDA):
44.878 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2p25.1 |
| Sequence: | 2; NC_000002.12 (10122568..10211010) |
Subcellular Localizations
Cytoplasm.
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Adenocarcinoma
- Pancreatic Neoplasm
- Malignant Neoplasm Of Pancreas
- Malignant Neoplasm Of Lung
- Neoplasm Metastasis
- Malignant Neoplasm Of Breast
- Mammary Neoplasms
- Lung Neoplasms
- Non-small Cell Lung Carcinoma
- Malignant Paraganglionic Neoplasm
Interacting Proteins
- CCNF
- FZR1
- RRM1
Pathways
- Translation
- Cell Proliferation
- Localization
- Cell Cycle
- Cell Growth
- Transport
- Rna Interference
- Nuclear Export
- Dna Repair
- Cell Cycle Arrest
- Drug Resistance
- Methylation
- Rna Processing
PTMs
- Phosphorylation
- Cleavage
- Methylation
Research Areas
- Cell Cycle and Replication
- Core ESC-Like Genes
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RRM2
bosterbio.com/bosterbio-gene-info-cards/RRM2
References
PMID: 1627826 by Pavloff N., et al. Sequence analysis of the large and small subunits of human ribonucleotide reductase.
PMID: 11978970 by Zhou B., et al. Characterization of the human ribonucleotide reductase M2 subunit gene; genomic structure and promoter analyses.
1 Publications of Boster RRM2 Antibodies & ELISA Kits
- PubMed ID: 25523932, Xu Lx, Li Zh, Tao Yf, Li Rh, Fang F, Zhao H, Li G, Li Yh, Wang J, Feng X, Pan J....
*More publications can be found for each product on its corresponding product page