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- Table of Contents
Facts about RuvB-like 1.
Human | |
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Gene Name: | RUVBL1 |
Uniprot: | Q9Y265 |
Entrez: | 8607 |
Belongs to: |
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RuvB family |
49 kDa TATA box-binding protein-interacting protein; 54 kDa erythrocyte cytosolic protein; EC 3.6.1; EC 3.6.4.12,49 kDa TBP-interacting protein; ECP54; INO80 complex subunit H; INO80HTIP49A; NMP 238; NMP238ECP-54; Nuclear matrix protein 238; Pontin 52; PONTIN; Pontin52; RuvB (E coli homolog)-like 1; RuvB-like 1 (E. coli); ruvB-like 1; RVB1; TATA binding protein interacting protein 49 kDa; TIH1; TIP49a; TIP49TAP54-alpha; TIP60-associated protein 54-alpha
Mass (kDA):
50.228 kDA
Human | |
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Location: | 3q21.3 |
Sequence: | 3; NC_000003.12 (128064611..128153914, complement) |
Ubiquitously expressed with high expression in heart, skeletal muscle and testis.
Nucleus matrix. Nucleus, nucleoplasm. Cytoplasm. Membrane. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Mainly localized in the nucleus, associated with nuclear matrix or in the nuclear cytosol, although it is also present in the cytoplasm and associated with the cell membranes. In prophase and prometaphase it is located at the centrosome and the branching microtubule spindles. After mitotic nuclear membrane disintigration it accumulates at the centrosome and sites of tubulin polymerization. As cells pass through metaphase and into telophase it is located close to the ce
PMID: 9588198 by Makino Y., et al. TIP49, homologous to the bacterial DNA helicase RuvB, acts as an autoantigen in human.
PMID: 9813143 by Holzmann K., et al. Identification and characterization of the ubiquitously occurring nuclear matrix protein NMP 238.