RNA-binding protein 25 Antibodies

AND RBM25 ELISA kits, RNA-binding protein 25 Proteins

Many biological assays use antibodies to detect RNA-binding protein 25, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RNA-binding protein 25 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RNA-binding protein 25 antibodies...

We validate the specificity of these antibodies to RNA-binding protein 25 by testing them on tissues known to express RBM25 positively and negatively. Browse below to find the RBM25 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for RNA-binding protein 25? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the RBM25 IHC Guide

RBM25 Infographic by Boster Bio

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Anti-RBM25 Antibody Picoband®

Western blot analysis of RBM25 using anti-RBM25 antibody (A07494-1)

IHC analysis of RBM25 using anti-RBM25 antibody (A07494-1)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A07494-1
100 µg/vial

RBM25 Overview

Facts about RNA-binding protein 25.

RBM25 3D structure. Source: alphafold

RNA-binding protein 25 (RBM25)

RNA-binding protein that functions as a regulator of alternative pre-mRNA splicing. Involved in apoptotic cell death through the regulation of the apoptotic factor BCL2L1 isoform expression.

Modulates the proportion of proapoptotic BCL2L1 isoform S to antiapoptotic BCL2L1 isoform L mRNA expression. When overexpressed, arouses proapoptotic BCL2L1 isoform S 5'-splice site (5'-ss) choice, whereas its depletion caused the accumulation of antiapoptotic BCL2L1 isoform L.

Gene Information

Human
Gene Name:	RBM25
Uniprot:	P49756
Entrez:	58517

Family

Belongs to:

No superfamily

Alternative Names

Arg/Glu/Asp-rich protein of 120 kDa; Arg/Glu/Asp-rich protein, 120 kDa; fSAP94; functional spliceosome-associated protein 94; MGC105088; MGC117168; NET52; Protein S164; RED120RNA-binding region-containing protein 7; RNA binding motif protein 25; RNA-binding motif protein 25; RNA-binding protein 25; RNA-binding region (RNP1, RRM) containing 7; RNPC7; S164; Snu71; U1 small nuclear ribonucleoprotein 1SNRP homolog

Molecular Weight

Mass (kDA):
100.185 kDA

Genomic Context


Human

Location:	14q24.2
Sequence:	14; NC_000014.9 (73058532..73123899)

Subcellular Localizations

Nucleus speckle. Cytoplasm. Colocalizes predominantly, with SFRS2 and LUC7L3 splicing factors, in nuclear speckles. Cytoplasmic localization is faint.

Diseases

Liver Diseases
Liver Failure, Chronic
Toxic Effect Of Carbon Tetrachloride
Liver Failure
Heart Failure
Liver Failure, Acute
Diabetes Mellitus
Fibrosis
Heart Diseases
Liver Cirrhosis, Experimental

Diabetes Mellitus, Insulin-dependent
Sudden Death
Hepatic Fibrosis
Liver Cirrhosis

Pathways

Mrna Splicing
Mrna Processing

PTMs

Acetylation
Isopeptide bond

Phosphoprotein
Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RBM25

References

PMID: 17560998 by Fortes P., et al. Identification and characterization of RED120: a conserved PWI domain protein with links to splicing and 3'-end formation.

PMID: 7596406 by Sherrington R., et al. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease.