This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
SART3 Antibodies
AND SART3 ELISA kits, SART3 Proteins
Many biological assays use antibodies to detect SART3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SART3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SART3 antibodies...
Designing an IHC experiment for SART3? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the SART3 IHC GuideSART3 Infographic by Boster Bio
All SART3 Products
Product
Figures
Specificity
Applications
Price
SART3 Overview
Facts about Squamous cell carcinoma antigen recognized by T-cells 3.
Squamous cell carcinoma antigen recognized by T-cells 3 (SART3)
U6 snRNP-binding protein that serves as a recycling factor of the splicing machinery. Promotes the initial reassembly of U4 and U6 snRNPs after their ejection from the spliceosome during its maturation (PubMed:12032085).
Also binds U6atac snRNPs and may function as a recycling factor for U4atac/U6atac spliceosomal snRNP, an initial step in the assembly of U12-type spliceosomal complex. The U12-type spliceosomal complex plays a role in the splicing of introns with non-canonical splice sites (PubMed:14749385).
Gene Information
| Human | |
|---|---|
| Gene Name: | SART3 |
| Uniprot: | Q15020 |
| Entrez: | 9733 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
DSAP1; hSART-3; KIAA0156squamous cell carcinoma antigen recognised by T cells 3; P100; p110; p110(nrb); RP11-13G14; SART-3; squamous cell carcinoma antigen recognized by T cells 3; squamous cell carcinoma antigen recognized by T-cells 3; Tat-interacting protein of 110 kDa; Tip110; TIP110MGC138188
Molecular Weight
Mass (kDA):
109.935 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12q23.3 |
| Sequence: | 12; NC_000012.12 (108522214..108561173, complement) |
Subcellular Localizations
Nucleus, nucleoplasm. Nucleus, Cajal body. Nucleus speckle. Cytoplasm.
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Malignant Neoplasm Of Prostate
- Adenocarcinoma
- Prostatic Neoplasms
- Colorectal Cancer
- Malignant Neoplasm Of Pancreas
- Malignant Tumor Of Colon
- Immunologic Deficiency Syndromes
- Esophageal Neoplasms
- Malignant Paraganglionic Neoplasm
Interacting Proteins
- RNPS1
Pathways
- Keratinization
- Immune Response
- Localization
- Pathogenesis
- Transport
- Protein Targeting
- Fertilization
- Humoral Immune Response
- Rna Capping
- Mrna Splicing
- Translation
- Organ Development
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SART3
bosterbio.com/bosterbio-gene-info-cards/SART3
References
PMID: 10463607 by Yang D., et al. Identification of a gene coding for a protein possessing shared tumor epitopes capable of inducing HLA-A24-restricted cytotoxic T lymphocytes in cancer patients.
PMID: 11959860 by Liu Y., et al. HIV-1 Tat protein-mediated transactivation of the HIV-1 long terminal repeat promoter is potentiated by a novel nuclear Tat-interacting protein of 110 kDa, Tip110.