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Sass6 Antibodies
AND Sass6 ELISA kits, Sass6 Proteins
Many biological assays use antibodies to detect Sass6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Sass6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Sass6 antibodies...
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Sass6 Infographic by Boster Bio
All Sass6 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, WB
$370
Cat # A05762-1
100 µg/vial
Cat # A05762-1
100 µg/vial
Sass6 Overview
Facts about Spindle assembly abnormal protein 6 homolog.
Spindle assembly abnormal protein 6 homolog (Sass6)
Central scaffolding component of the centrioles making sure their 9-fold symmetry. Required for centrosome biogenesis and duplication: required both for mother-centriole-dependent centriole duplication and deuterosome-dependent centriole amplification in multiciliated cells (PubMed:24240477).
Required for the recruitment of STIL into the procentriole and for STIL- mediated centriole amplification (By similarity). .
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Sass6 |
| Uniprot: | Q80UK7 |
| Entrez: | 72776 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
DKFZp761A078; FLJ22097; HsSAS-6; MGC119440; SAS-6; SAS6hsSAS-6; spindle assembly 6 homolog (C. elegans); spindle assembly abnormal protein 6 homolog
Molecular Weight
Mass (kDA):
74.054 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 3|3 G1 |
| Sequence: | 3; |
Diseases
- Primary Microcephaly
- Microcephaly
- Cell Transformation, Neoplastic
Pathways
- Cell Cycle
- Centrosome Duplication
- Mitosis
- Rna Interference
- Localization
- Centriole Replication
PTMs
Research Areas
- Cell Cycle and Replication
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Sass6
bosterbio.com/bosterbio-gene-info-cards/Sass6
References
PMID: 24240477 by Zhao H., et al. The Cep63 paralogue Deup1 enables massive de novo centriole biogenesis for vertebrate multiciliogenesis.