Secernin-1 Antibodies

AND SCRN1 ELISA kits, Secernin-1 Proteins

Many biological assays use antibodies to detect Secernin-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Secernin-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Secernin-1 antibodies...

We validate the specificity of these antibodies to Secernin-1 by testing them on tissues known to express SCRN1 positively and negatively. Browse below to find the SCRN1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SCRN1 Infographic by Boster Bio

All SCRN1 Products

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Anti-Secernin-1 SCRN1 Antibody

Western blot analysis of SCRN1 in human kidney tissue lysate with SCRN1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide

Immunohistochemistry of SCRN1 in human kidney tissue with SCRN1 antibody at 5 μg/mL

Immunofluorescence of SCRN1 in Human Kidney cells with SCRN1 antibody at 20 μg/mL

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$481
Cat # A10002
0.1 mg

SCRN1 (NM_001145513) Human Recombinant Protein

$1249
Cat # PROTQ12765
20 µg

Anti-SCRN1 Mouse Monoclonal Antibody [Clone ID: OTI1F2]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SCRN1 (Right lane) cDNA for 48 hrs and lysed

Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-SCRN1 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human)

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-SCRN1 mouse monoclonal antibody

Human, Monkey, Mouse, Rat

IHC, WB

$523
Cat # M10002
100 µl

Anti-SCRN1 Antibody Picoband®

Western blot analysis of SCRN1 using anti-SCRN1 antibody (A10002-1)

IHC analysis of SCRN1 using anti-SCRN1 antibody (A10002-1)

Human, Mouse, Rat

IF, IHC, ICC, WB

$370
Cat # A10002-1
100 μg/vial

SCRN1 Overview

Facts about Secernin-1.

SCRN1 3D structure. Source: alphafold

Secernin-1 (SCRN1)

Regulates exocytosis in mast cells. Increases both the extent of secretion and the sensitivity of mast cells to stimulation with calcium (By similarity).

. .

Gene Information

Human
Gene Name:	SCRN1
Uniprot:	Q12765
Entrez:	9805

Family

Belongs to:

peptidase C69 family

Alternative Names

KIAA0193SES1; secernin 1; secernin-1

Molecular Weight

Mass (kDA):
46.382 kDA

Genomic Context


Human

Location:	7p14.3
Sequence:	7; NC_000007.14 (29920103..29990289, complement)

Subcellular Localizations

Cytoplasm.

Diseases

Malignant Neoplasms
Malignant Neoplasm Of Stomach
Neoplasms
Stomach Neoplasms
Colorectal Neoplasms
Colorectal Cancer
Adenoma
Neoplasm Metastasis
Colonic Neoplasms
Synovial Sarcoma
Malignant Tumor Of Colon

Sarcoma
Carcinoma
Carcinogenesis
Colon Adenoma
Aortic Aneurysm, Thoracic
Lymphocytic Choriomeningitis

Interacting Proteins

GORASP1

Pathways

Cell Growth
Methylation
Sertoli Cell Differentiation
Regulation Of Exocytosis
Cell Differentiation
Sex Determination
Gonad Development

Exocytosis
Secretion

PTMs

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SCRN1

References

PMID: 16630140 by Suda T., et al. Identification of secernin 1 as a novel immunotherapy target for gastric cancer using the expression profiles of cDNA microarray.

PMID: 11921445 by O'Neill E.E., et al. Towards complete analysis of the platelet proteome.