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- Table of Contents
Syntenin-2 Antibodies
AND SDCBP2 ELISA kits, Syntenin-2 Proteins
Many biological assays use antibodies to detect Syntenin-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Syntenin-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Syntenin-2 antibodies...
Designing an IHC experiment for Syntenin-2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the SDCBP2 IHC GuideSDCBP2 Infographic by Boster Bio
All SDCBP2 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A13491-2
100 μg/vial
Cat # A13491-2
100 μg/vial
SDCBP2 Overview
Facts about Syntenin-2.
Syntenin-2 (SDCBP2)
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Gene Information
| Human | |
|---|---|
| Gene Name: | SDCBP2 |
| Uniprot: | Q9H190 |
| Entrez: | 27111 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
FLJ12256; SITAC18ST-2; syndecan binding protein (syntenin) 2; Syndecan-binding protein 2; syntenin-2
Molecular Weight
Mass (kDA):
31.594 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 20p13 |
| Sequence: | 20; NC_000020.11 (1309909..1329139, complement) |
Tissue Specificity
Preferentially expressed in cells of the digestive tract (PubMed:11102519). Low expression in skeletal muscle and kidney (PubMed:11102519). Detected in differentiated keratinocytes of normal and malignant epithelium (PubMed:22623796). In healthy skin, expression is localized in suprabasal epidermal layers (PubMed:22623796).
Subcellular Localizations
Cytoplasm. Nucleus, nucleolus. Nucleus, nucleoplasm. Cell membrane. Nucleus speckle. Associates with intracellular membranes and enriched in the apical region of the cell and in intracellular compartments (PubMed:11102519). Colocalizes with TM4SF1 in the apical region of the cell (PubMed:11102519). Predominantly targeted to nuclear PIP2 pools. Shuttles between several subcellular compartments (PubMed:15961997). PIP2 plays an important role in the distribution of SDCBP2 (PubMed:23300061).
Diseases
- Basal Cell Carcinoma
- Malignant Squamous Cell Neoplasm
- Tissue Adhesions
- Carcinoma
Interacting Proteins
- ADAP1
- ARF4
- CT45A3
- EIF1AD
- FAM133A
- FAM13C
- FAM9B
- FBXO28
- LGALS14
- LGALS2
Pathways
- Cell Adhesion
- Cell Division
Research Areas
- Neuroscience
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SDCBP2
bosterbio.com/bosterbio-gene-info-cards/SDCBP2
References
PMID: 11152476 by Koroll M., et al. The neural cell recognition molecule neurofascin interacts with syntenin-1 but not with syntenin-2, both of which reveal self- associating activity.
PMID: 11102519 by Borrell-Pages M., et al. The carboxy-terminal cysteine of the tetraspanin L6 antigen is required for its interaction with SITAC, a novel PDZ protein.