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- Table of Contents
SEC22B Antibodies
AND SEC22B ELISA kits, SEC22B Proteins
Many biological assays use antibodies to detect SEC22B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SEC22B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SEC22B antibodies...
Designing a Western blot for SEC22B? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the SEC22B Western Blot GuideSEC22B Infographic by Boster Bio
All SEC22B Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A06284-2
100 μg/vial
Cat # A06284-2
100 μg/vial
SEC22B Overview
Facts about Vesicle-trafficking protein SEC22b.
Vesicle-trafficking protein SEC22b (SEC22B)
SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex in addition to Golgi-derived retrograde transport vesicles with the ER. .
Gene Information
| Human | |
|---|---|
| Gene Name: | SEC22B |
| Uniprot: | O75396 |
| Entrez: | 9554 |
Family
| Belongs to: |
|---|
| synaptobrevin family |
Alternative Names
ERS24; ERS-24sec22b; SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene); SEC22 vesicle trafficking protein homolog B (S. cerevisiae); SEC22 vesicle trafficking protein-like 1 (S. cerevisiae); SEC22 vesicle trafficking protein-like 1; SEC22 vesicle-trafficking protein homolog B; SEC22 vesicle-trafficking protein-like 1; SEC22, vesicle trafficking protein (S. cerevisiae)-like 1; SEC22L1ER-Golgi SNARE of 24 kDa; vesicle-trafficking protein SEC22b
Molecular Weight
Mass (kDA):
24.593 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p12 |
| Sequence: | 1; NC_000001.11 (120150898..120176520, complement) |
Subcellular Localizations
Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane. Golgi apparatus, cis-Golgi network membrane. Golgi apparatus, trans-Golgi network membrane. Melanosome. Concentrated most in the intermediate compartment/cis-Golgi network and the cis-Golgi cisternae 1 and 2. Greatly reduced in concentration at the trans end of the Golgi apparatus (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065).
Diseases
- Legionnaires' Disease
- Murine Hepatitis
- Impaired Phagocytosis
- Toxoplasmosis
- Escherichia Coli Infections
- Stomatitis
- Parkinson Disease
- Dysplasia
- Osteoarthropathy
- Neoplasms
- Cell Invasion
- Hereditary Diseases
- Coronavirus Infections
Interacting Proteins
- STX18
- STX4
Pathways
- Transport
- Membrane Fusion
- Secretory Pathway
- Phagocytosis
- Localization
- Secretion
- Snare Complex Assembly
- Vesicle Transport
- Endocytosis
- Vesicle Docking
- Golgi To Plasma Membrane Transport
- Clathrin-mediated Endocytosis
- Phagosome Formation
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SEC22B
bosterbio.com/bosterbio-gene-info-cards/SEC22B
References
PMID: 9653160 by Mao M., et al. Identification of genes expressed in human CD34(+) hematopoietic stem/progenitor cells by expressed sequence tags and efficient full- length cDNA cloning.
PMID: 15272311 by Nakajima K., et al. Involvement of BNIP1 in apoptosis and endoplasmic reticulum membrane fusion.