SEC23B Antibodies

AND SEC23B ELISA kits, SEC23B Proteins

Many biological assays use antibodies to detect SEC23B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SEC23B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SEC23B antibodies...

We validate the specificity of these antibodies to SEC23B by testing them on tissues known to express SEC23B positively and negatively. Browse below to find the SEC23B antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for SEC23B? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the SEC23B Western Blot Guide

SEC23B Infographic by Boster Bio

All SEC23B Products

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Specificity

Applications

Price

Anti-SEC23B Antibody Picoband®

Western blot analysis of SEC23B using anti-SEC23B antibody (A05847-3)

Flow Cytometry analysis of SiHa cells using anti-SEC23B antibody (A05847-3)

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A05847-3
100 μg/vial

SEC23B (NM_006363) Human Over-expression Lysate

SEC23B Human Over-expression Lysates NM_006363

Human

$628
Cat # LS010483
20 µg, 100 µg

SEC23B (NM_032986) Human Recombinant Protein

Coomassie blue staining of purified SEC23B protein

$1249
Cat # PROTQ15437
20 µg

SEC23B Overview

Facts about Protein transport protein Sec23B.

SEC23B 3D structure. Source: alphafold

Protein transport protein Sec23B (SEC23B)

Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two major functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the choice of cargo molecules for their transport to the Golgi complex.

Gene Information

Human
Gene Name:	SEC23B
Uniprot:	Q15437
Entrez:	10483

Family

Belongs to:

SEC23/SEC24 family

Alternative Names

CDAII; CDA-II; CDAN2; congenital dyserythropoietic anemia, type II; HEMPASSec23 (S. cerevisiae) homolog B; protein transport protein Sec23B; Sec23 homolog B (S. cerevisiae); SEC23-like protein B; SEC23-related protein B; transport protein SEC23B

Molecular Weight

Mass (kDA):
86.479 kDA

Genomic Context


Human

Location:	20p11.23
Sequence:	20; NC_000020.11 (18507482..18561415)

Tissue Specificity

Ubiquitously expressed.

Subcellular Localizations

Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytosol.

Diseases

Congenital Dyserythropoietic Anemia
Anemia
Congenital Dyserythropoietic Anemia, Type Ii
Iron Overload
Hyperplasia
Dysplasia
Icterus
Hydrops Fetalis
Mutation Abnormality
Coagulation Factor Deficiency

Carcinoma
Endoplasmic Reticulum Stress
Hereditary Spherocytosis
Fibrosis
Hemolysis (disorder)

Interacting Proteins

CPSF7
DTX2
FATE1
HOXA3
PRRC1

SEC24D
SYNE4

Pathways

Transport
Secretory Pathway
Pathogenesis
Localization
Glycosylation
Protein Transport
Erythrocyte Development
Hemopoiesis
Cytokinesis
Cell Maturation
Ribosome Biogenesis
Translation

Coagulation
Chondrocyte Development
Protein Folding
Erythrocyte Maturation
Chromatin Assembly
Secretion

PTMs

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SEC23B

References

PMID: 8898360 by Paccaud J.-P., et al. Cloning and functional characterization of mammalian homologues of the COPII component Sec23.

PMID: 19621418 by Bianchi P., et al. Congenital dyserythropoietic anemia type II (CDAII) is caused by mutations in the SEC23B gene.