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- Table of Contents
SEC31A Antibodies
AND SEC31A ELISA kits, SEC31A Proteins
Many biological assays use antibodies to detect SEC31A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SEC31A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SEC31A antibodies...
Designing an IHC experiment for SEC31A? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the SEC31A IHC GuideSEC31A Infographic by Boster Bio
All SEC31A Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A04582
100 μg/vial
Cat # A04582
100 μg/vial
SEC31A Overview
Facts about Protein transport protein Sec31A.
Protein transport protein Sec31A (SEC31A)
Part of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER) (PubMed:10788476). The coat has two major functions, the physical deformation of the endoplasmic reticulum membrane into vesicles along with the choice of cargo molecules (By similarity).
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Gene Information
| Human | |
|---|---|
| Gene Name: | SEC31A |
| Uniprot: | O94979 |
| Entrez: | 22872 |
Family
| Belongs to: |
|---|
| WD repeat SEC31 family |
Alternative Names
ABP125ABP130KIAA0905Web1-like protein; DKFZp686N07171; HSPC334; MGC90305; protein transport protein Sec31A; protein-transport protein SEC31; SEC31 homolog A (S. cerevisiae); SEC31L1; SEC31-like 1 (S. cerevisiae); SEC31-like 1; SEC31-like protein 1; SEC31-related protein A; yeast Sec31p homolog
Molecular Weight
Mass (kDA):
133.015 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 4q21.22 |
| Sequence: | 4; NC_000004.12 (82818509..82900571, complement) |
Tissue Specificity
Abundantly and ubiquitously expressed.
Subcellular Localizations
Cytoplasm. Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein. Cytoplasm, cytosol. Associates with membranes in a GTP-dependent manner (By similarity). Localizes to endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER) (PubMed:25201882, PubMed:28442536, PubMed:17428803).
Diseases
- Dysplasia
- Lymphoma
- Craniofacial Abnormalities
- B-cell Lymphomas
- Stomatitis
- Vesicular Stomatitis
- Diffuse Large B-cell Lymphoma
- Hereditary Diseases
- Classical Hodgkin's Lymphoma
- 4q Partial Monosomy Syndrome
- Developmental Delay (disorder)
- Cleft Palate
- Acute Lymphocytic Leukemia
Interacting Proteins
- PDCD6
- REL
Pathways
- Transport
- Secretory Pathway
- Localization
- Protein Transport
- Secretion
- Mrna Splicing
- Cell Proliferation
- Membrane Fission
PTMs
- Biotinylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SEC31A
bosterbio.com/bosterbio-gene-info-cards/SEC31A
References
PMID: 10788476 by Tang B.L., et al. Mammalian homologues of yeast sec31p. An ubiquitously expressed form is localized to endoplasmic reticulum (ER) exit sites and is essential for ER-Golgi transport.
PMID: 10574704 by Shugrue C.A., et al. Identification of the putative mammalian orthologue of Sec31P, a component of the COPII coat.