Semaphorin-6D Antibodies

AND SEMA6D ELISA kits, Semaphorin-6D Proteins

Many biological assays use antibodies to detect Semaphorin-6D, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Semaphorin-6D in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Semaphorin-6D antibodies...

We validate the specificity of these antibodies to Semaphorin-6D by testing them on tissues known to express SEMA6D positively and negatively. Browse below to find the SEMA6D antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SEMA6D Infographic by Boster Bio

All SEMA6D Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Human SEMA6D ELISA Kit PicoKine®

7 Q&As

Human

ELISA

$499
Cat # EK2060
96 wells/kit, with removable strips.

Anti-SEM6D SEMA6D Antibody

Human, Mouse

ELISA, WB

$380
Cat # A08244
100ul

SEMA6D (NM_153618) Human Over-expression Lysate

SEMA6D Human Over-expression Lysates NM_024966

Human

$960
Cat # LS080031
20 µg, 100 µg

SEMA6D Overview

Facts about Semaphorin-6D.

SEMA6D 3D structure. Source: alphafold

Semaphorin-6D (SEMA6D)

Shows growth cone collapsing activity on dorsal root ganglion (DRG) neurons in vitro. May be a stop signal for the DRG neurons in their target areas, and possibly also for other neurons.

May also be involved in the maintenance and remodeling of neuronal connections. .

Gene Information

Human
Gene Name:	SEMA6D
Uniprot:	Q8NFY4
Entrez:	80031

Family

Belongs to:

semaphorin family

Alternative Names

KIAA1479FLJ11598; sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D; Sema6D; Semaphorin 6D; semaphorin-6D

Molecular Weight

Mass (kDA):
119.872 kDA

Genomic Context


Human

Location:	15q21.1
Sequence:	15; NC_000015.10 (47184089..47774228)

Subcellular Localizations

[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Cell membrane; Single-pass type I membrane protein.; [Isoform 3]: Cell membrane; Single-pass type I membrane protein.; [Isoform 4]: Cell membrane; Single-pass type I membrane protein.; [Isoform 5]: Cell membrane; Single-pass type I membrane protein.; [Isoform 7]: Cytoplasm.

Diseases

Nervousness
Malignant Neoplasms
Neoplasms
Cell Transformation, Neoplastic
Neurodegenerative Disorders
Ataxia
Pleural Neoplasms
Spastic Paraplegia, Hereditary
Malignant Pleural Mesothelioma
Neoplasm Invasiveness
Spastic Paraplegia, Hereditary, Autosomal Recessive
Carcinogenesis

Pleural Mesothelioma
Congenital Heart Defects
Tumor Angiogenesis
Paraplegia
Colorectal Cancer
Spinal Cord Diseases

Pathways

Axon Guidance
Rna Interference
Protein Phosphorylation
Neural Tube Closure
Cell Proliferation
Cell Migration
Gastrulation
Convergent Extension
Oocyte Maturation
Localization
Tube Closure
Cardiac Chamber Formation
Cell Motility

Cell Death
T Cell Proliferation
Angiogenesis
Invasive Growth
Spinal Cord Development
Meiosis
Organ Growth

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SEMA6D

References

PMID: 12110693 by Qu X., et al. Identification, characterization, and functional study of the two novel human members of the semaphorin gene family.