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- Table of Contents
Designing an IHC experiment for SEPHS1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the SEPHS1 IHC GuideFacts about Selenide, water dikinase 1.
| Human | |
|---|---|
| Gene Name: | SEPHS1 |
| Uniprot: | P49903 |
| Entrez: | 22929 |

| Belongs to: |
|---|
| selenophosphate synthase 1 family |

EC 2.7.9.3; MGC4980; SELD; Selenium donor protein 1; Selenophosphate synthase 1; selenophosphate synthetase 1 +E9a; selenophosphate synthetase 1 delta E2; selenophosphate synthetase 1 delta E8; selenophosphate synthetase 1 major; selenophosphate synthetase 1; SPS1selenophosphate synthetase 1 +E9; water dikinase 1
Mass (kDA):
42.911 kDA

| Human | |
|---|---|
| Location: | 10p13 |
| Sequence: | 10; NC_000010.11 (13317428..13348298, complement) |
Isoform 1 and isoform 2 are gradually expressed during the cell cycle until G2/M phase and then decreased. Isoform 3 is gradually expressed during the cell cycle until S phase and then decreased.
[Isoform 1]: Cell membrane. Nucleus membrane.; [Isoform 2]: Cytoplasm.; [Isoform 3]: Cytoplasm.; [Isoform 4]: Cytoplasm.






PMID: 7665581 by Low S.C., et al. Cloning and functional characterization of human selenophosphate synthetase, an essential component of selenoprotein synthesis.
PMID: 20471958 by Kim J.Y., et al. Human selenophosphate synthetase 1 has five splice variants with unique interactions, subcellular localizations and expression patterns.