SERPINB2 Antibodies

AND SERPINB2 ELISA kits, SERPINB2 Proteins

Many biological assays use antibodies to detect SERPINB2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SERPINB2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SERPINB2 antibodies...

We validate the specificity of these antibodies to SERPINB2 by testing them on tissues known to express SERPINB2 positively and negatively. Browse below to find the SERPINB2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for SERPINB2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the SERPINB2 Western Blot Guide

SERPINB2 Infographic by Boster Bio

All SERPINB2 Products

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Product

Figures

Specificity

Applications

Price

Anti-SerpinB2 Antibody Picoband®

Anti-SerpinB2 Picoband antibody, PB9355, Western blottingAll lanes: Anti SerpinB2 (PB9355) at 0

Human

IHC, WB

$370
Cat # PB9355
100 μg/vial

SERPINB2 (NM_001143818) Human Over-expression Lysate

SERPINB2 Human Over-expression Lysates NM_001143818

Human

$628
Cat # LS005055
20 µg, 100 µg

SERPINB2 (NM_001143818) Human Recombinant Protein

$1249
Cat # PROTP05120
20 µg

SERPINB2 Overview

Facts about Plasminogen activator inhibitor 2.

SERPINB2 3D structure. Source: alphafold

Plasminogen activator inhibitor 2 (SERPINB2)

Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell- based PAI-1.

Gene Information

Human
Gene Name:	SERPINB2
Uniprot:	P05120
Entrez:	5055

Family

Belongs to:

serpin family

Alternative Names

HsT1201; Monocyte Arg-serpin; PAI; PAI2; PAI2Urokinase inhibitor; Placental plasminogen activator inhibitor; PLANH2; PLANH2PAI-2; plasminogen activator inhibitor 2; plasminogen activator inhibitor, type II (arginine-serpin); serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2; Serpin B2; serpin peptidase inhibitor, clade B (ovalbumin), member 2; Urokinase Inhibitor

Molecular Weight

Mass (kDA):
46.596 kDA

Genomic Context


Human

Location:	18q21.33-q22.1
Sequence:	18; NC_000018.10 (63887705..63903890)

Subcellular Localizations

Cytoplasm. Secreted, extracellular space.

Diseases

Neoplasms
Malignant Neoplasms
Inflammation
Cell Invasion
Retinoblastoma
Neoplasm Metastasis
Malignant Paraganglionic Neoplasm
Carcinogenesis
Tumor Angiogenesis
Papilloma
Tissue Adhesions
Neoplasm Invasiveness

Carcinoma
Fibrosis
Tumor Progression
Asthma
Skin Neoplasms
Hypertensive Disease
Lupus Erythematosus, Systemic

Pathways

Cell Death
Cell Migration
Cell Growth
Endocytosis
Angiogenesis
Cell Adhesion
Programmed Cell Death
Proteolysis
Immune Response
Cell Proliferation
Plasminogen Activation
Pathogenesis
Secretion

Transport
Cell Activation
Muscle Cell Migration
Gene Silencing
Adaptive Immune Response
Mrna Destabilization
Regulation Of Programmed Cell Death

PTMs

Phosphorylation

Cleavage

Glycosylation

Research Areas

Apoptosis
Cancer

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SERPINB2

References

PMID: 3029122 by Ye R.D., et al. cDNA cloning and expression in Escherichia coli of a plasminogen activator inhibitor from human placenta.

PMID: 3325828 by Schleuning W.-D., et al. Plasminogen activator inhibitor 2: regulation of gene transcription during phorbol ester-mediated differentiation of U-937 human histiocytic lymphoma cells.