SHMT1 Antibodies

AND SHMT1 ELISA kits, SHMT1 Proteins

Many biological assays use antibodies to detect SHMT1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SHMT1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SHMT1 antibodies...

We validate the specificity of these antibodies to SHMT1 by testing them on tissues known to express SHMT1 positively and negatively. Browse below to find the SHMT1 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SHMT1 Infographic by Boster Bio

All SHMT1 Products

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Specificity

Applications

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Anti-SHMT1 Antibody

Western blot analysis of extracts of various cell lines, using SHMT1 antibody at 1:1512 dilution

Immunohistochemistry of paraffin-embedded human stomach using SHMT1 antibody at dilution of 1:100

Immunohistochemistry of paraffin-embedded rat kidney using SHMT1 antibody at dilution of 1:100

Human, Mouse, Rat

IHC, WB

$405
Cat # A02944
100ul

Anti-SHMT1 Antibody Picoband®

Western blot analysis of SHMT1 using anti-SHMT1 antibody (A02944-1)

IHC analysis of SHMT1 using anti-SHMT1 antibody (A02944-1)

Human, Monkey, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A02944-1
100 μg/vial

Anti-SHMT1 Antibody Picoband® (monoclonal, 9C7)

Western blot analysis of SHMT1 using anti-SHMT1 antibody (M02944)

IHC analysis of SHMT1 using anti-SHMT1 antibody (M02944)

IF analysis of SHMT1 using anti-SHMT1 antibody (M02944)

Human, Monkey, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M02944
100 μg/vial

SHMT1 (NM_004169) Human Recombinant Protein

Coomassie blue staining of purified SHMT1 protein

$1249
Cat # PROTP34896
20 µg

SHMT1 (NM_004169) Human Over-expression Lysate

SHMT1 Human Over-expression Lysates NM_004169

Human

$628
Cat # LS006470
20 µg, 100 µg

SHMT1 Overview

Facts about Serine hydroxymethyltransferase, cytosolic.

SHMT1 3D structure. Source: alphafold

Serine hydroxymethyltransferase, cytosolic (SHMT1)

Interconversion of serine and glycine (PubMed:8505317, PubMed:24698160). .

Gene Information

Human
Gene Name:	SHMT1
Uniprot:	P34896
Entrez:	6470

Family

Belongs to:

SHMT family

Alternative Names

14 kDa protein; CSHMT; cytoplasmic serine hydroxymethyltransferase; Glycine hydroxymethyltransferase; MGC15229; MGC24556; serine hydroxymethyltransferase 1 (soluble); serine hydroxymethyltransferase, cytosolic; Serine methylase; SHMTEC 2.1.2.1

Molecular Weight

Mass (kDA):
53.083 kDA

Genomic Context


Human

Location:	17p11.2
Sequence:	17; NC_000017.11 (18327860..18363563, complement)

Subcellular Localizations

Cytoplasm.

Diseases

5,10-methylenetetrahydrofolate Reductase Deficiency
Malignant Neoplasms
Acute Lymphocytic Leukemia
Leukemia
Neoplasms
Lymphoma
L1 Acute Lymphoblastic Leukemia
Cholangiocarcinoma
Lymphoma, Non-hodgkin
Folic Acid Deficiency
Carcinoma
Malignant Neoplasm Of Breast
Mammary Neoplasms

Lymphoma, Follicular
Genomic Instability
Choline Deficiency
Congenital Abnormality
Prostatic Neoplasms
Diffuse Large B-cell Lymphoma
Colorectal Cancer

Interacting Proteins

MAPK9
SULT1A3

Pathways

Methylation
Pathogenesis
Transport
Aging
Translation
Cell Cycle
Dna Repair
Dna Methylation
Localization
S Phase
Neural Tube Closure
Nuclear Import
Prepulse Inhibition

Tube Closure
Dna Replication
Photorespiration
Amino Acid Homeostasis
Nuclear Export
Cell Cycle Arrest
Nuclear Transport

PTMs

Methylation
Sumoylation

Phosphorylation
Cleavage

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SHMT1

References

PMID: 8505317 by Garrow T.A., et al. Cloning of human cDNAs encoding mitochondrial and cytosolic serine hydroxymethyltransferases and chromosomal localization.

PMID: 9056951 by Chave K.J., et al. Isolation and characterisation of human genomic sequences encoding cytosolic serine hydroxymethyltransferase.