SLC25A13 Antibodies

AND SLC25A13 ELISA kits, SLC25A13 Proteins

Many biological assays use antibodies to detect SLC25A13, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SLC25A13 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SLC25A13 antibodies...

We validate the specificity of these antibodies to SLC25A13 by testing them on tissues known to express SLC25A13 positively and negatively. Browse below to find the SLC25A13 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for SLC25A13? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the SLC25A13 IHC Guide

SLC25A13 Infographic by Boster Bio

All SLC25A13 Products

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Anti-Citrin/SLC25A13 Antibody Picoband®

Western blot analysis of Citrin/SLC25A13 using anti-Citrin/SLC25A13 antibody (A03476-2)

IHC analysis of Citrin/SLC25A13 using anti-Citrin/SLC25A13 antibody (A03476-2)

+16

Human, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A03476-2
100 μg/vial

SLC25A13 (NM_014251) Human Over-expression Lysate

Human

$628
Cat # LS010165
20 µg, 100 µg

SLC25A13 Overview

Facts about Calcium-binding mitochondrial carrier protein Aralar2.

SLC25A13 3D structure. Source: alphafold

Calcium-binding mitochondrial carrier protein Aralar2 (SLC25A13)

Mitochondrial and calcium-binding carrier that catalyzes the calcium-dependent exchange of cytoplasmic glutamate with mitochondrial aspartate across the mitochondrial inner membrane (PubMed:11566871, PubMed:25410934). May have a function in the urea cycle (PubMed:11566871).

Gene Information

Human
Gene Name:	SLC25A13
Uniprot:	Q9UJS0
Entrez:	10165

Family

Belongs to:

mitochondrial carrier (TC 2.A.29) family

Alternative Names

ARALAR2CTLN2; calcium-binding mitochondrial carrier protein Aralar2; CITRIN; Mitochondrial aspartate glutamate carrier 2; Solute carrier family 25 member 13; solute carrier family 25, member 13 (citrin)

Molecular Weight

Mass (kDA):
74.176 kDA

Genomic Context


Human

Location:	7q21.3
Sequence:	7; NC_000007.14 (96120220..96322147, complement)

Tissue Specificity

High levels in liver and low levels in kidney, pancreas, placenta, heart and brain.

Subcellular Localizations

Mitochondrion inner membrane; Multi-pass membrane protein.

Diseases

Citrullinemia
Intrahepatic Cholestasis
Cholestasis
Citrullinemia, Type Ii, Neonatal-onset
Hyperammonemia
Icterus
Hepatitis
Fatty Liver
Neonatal Hepatitis
Liver Diseases
Atresia
Hypoglycemia

Hypoproteinemia
Biliary Atresia
Galactosemias
Comatose
Inborn Errors Of Metabolism
Failure To Thrive
Encephalopathies

Pathways

Urea Cycle
Gluconeogenesis
Pathogenesis
Malate-aspartate Shuttle
Coagulation
Transport
Glycolysis
Natural Killer Cell Mediated Cytotoxicity
Endochondral Ossification
Stem Cell Differentiation
Ossification
Localization
Regeneration

Mesenchymal Stem Cell Differentiation
Aspartate Transport
Antigen Processing And Presentation
Cell Differentiation
Liver Regeneration
Fatty Acid Oxidation
Excretion

PTMs

Oxidation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC25A13

References

PMID: 10369257 by Kobayashi K., et al. The gene mutated in adult-onset type II citrullinaemia encodes a putative mitochondrial carrier protein.

PMID: 10642534 by Del Arco A., et al. Characterization of a second member of the subfamily of calcium- binding mitochondrial carriers expressed in human non-excitable tissues.