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- Table of Contents
SLC40A1 Antibodies
AND SLC40A1 ELISA kits, SLC40A1 Proteins
Many biological assays use antibodies to detect SLC40A1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SLC40A1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SLC40A1 antibodies...
Designing a Western blot for SLC40A1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the SLC40A1 Western Blot GuideDesigning an IHC experiment for SLC40A1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the SLC40A1 IHC GuideSLC40A1 Infographic by Boster Bio
All SLC40A1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, WB
$370
Cat # A01953-2
100 μg/vial
Cat # A01953-2
100 μg/vial
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01953-1
100 μg
Cat # M01953-1
100 μg
Human, Rat
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01953
100 μg
Cat # M01953
100 μg
SLC40A1 Overview
Facts about Solute carrier family 40 member 1.
Solute carrier family 40 member 1 (SLC40A1)
May be involved in iron export from duodenal epithelial cell and also in transfer of iron between maternal and fetal circulation. Mediates iron efflux in the presence of a ferroxidase (hephaestin and/or ceruloplasmin).
.
Gene Information
| Human | |
|---|---|
| Gene Name: | SLC40A1 |
| Uniprot: | Q9NP59 |
| Entrez: | 30061 |
Family
| Belongs to: |
|---|
| ferroportin (FP) (TC 2.A.100) family |
Alternative Names
Ferroportin; Ferroportin-1; FPN1; FPN1IREG1ferroportin 1; HFE4; HFE4ferroportin-1; IREG1; Iron-regulated transporter 1; member 3; MST079; MTP1; putative ferroportin 1 variant IIIB; SLC11A3; SLC11A3iron regulated gene 1; SLC40A1; solute carrier family 11 (proton-coupled divalent metal ion transporters); solute carrier family 40 (iron-regulated transporter), member 1; solute carrier family 40 member 1
Molecular Weight
Mass (kDA):
62.542 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2q32.2 |
| Sequence: | 2; NC_000002.12 (189560590..189580811, complement) |
Tissue Specificity
Detected in erythrocytes (at protein level). Expressed in placenta, intestine, muscle and spleen.
Subcellular Localizations
Cell membrane; Multi-pass membrane protein. Localized to the basolateral membrane of polarized epithelial cells.
Diseases
- Hemochromatosis
- Iron Overload
- Hereditary Hemochromatosis
- Anemia
- Liver Cirrhosis
- Diabetes Mellitus
- Juvenile Hemochromatosis
- Iron Metabolism Disorders
- Hereditary Diseases
- Cardiomyopathies
- Malignant Neoplasms
- Hepatitis
- Tuberculosis
Interacting Proteins
- APP
Pathways
- Transport
- Localization
- Pathogenesis
- Pigmentation
- Inflammatory Response
- Endoderm Formation
- Cytolysis
- Gastrulation
- Intestinal Absorption
- Ureteric Bud Formation
- Reverse Transcription
PTMs
Research Areas
- Cancer
- Lipid and Metabolism
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC40A1
bosterbio.com/bosterbio-gene-info-cards/SLC40A1
References
PMID: 10747949 by Abboud S., et al. A novel mammalian iron-regulated protein involved in intracellular iron metabolism.
PMID: 10882071 by McKie A.T., et al. A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation.