SLITRK4 Antibodies

AND SLITRK4 ELISA kits, SLITRK4 Proteins

Many biological assays use antibodies to detect SLITRK4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SLITRK4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SLITRK4 antibodies...

We validate the specificity of these antibodies to SLITRK4 by testing them on tissues known to express SLITRK4 positively and negatively. Browse below to find the SLITRK4 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SLITRK4 Infographic by Boster Bio

All SLITRK4 Products

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Applications

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Anti-SLIT and NTRK-like protein 4 Slitrk4 Antibody

Western blot analysis of Slitrk4 in mouse brain tissue lysate with Slitrk4 antibody at (A) 0

Immunohistochemistry of Slitrk4 in human brain tissue with Slitrk4 antibody at 2

Immunofluorescence of slitrk4 in human brain tissue with slitrk4 antibody at 20 μg/mL

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$481
Cat # A14468
0.1 mg

SLITRK4 (NM_173078) Human Over-expression Lysate

Human

$628
Cat # LS139065
20 µg, 100 µg

Anti-SLITRK4 Antibody

Human, Mouse, Rat

ELISA, WB

$370
Cat # A14468-1
100 μl/vial

SLITRK4 Overview

Facts about SLIT and NTRK-like protein 4.

SLITRK4 3D structure. Source: alphafold

SLIT and NTRK-like protein 4 (SLITRK4)

It's involved in synaptogenesis and promotes synapse differentiation (PubMed:27812321). Suppresses neurite outgrowth (By similarity).

Gene Information

Human
Gene Name:	SLITRK4
Uniprot:	Q8IW52
Entrez:	139065

Family

Belongs to:

SLITRK family

Alternative Names

DKFZp547M2010; SLIT and NTRK-like family, member 4; SLIT and NTRK-like protein 4; slit and trk like gene 4; SLITRK4

Molecular Weight

Mass (kDA):
94.331 kDA

Genomic Context


Human

Location:	Xq27.3
Sequence:	X; NC_000023.11 (143622790..143636101, complement)

Tissue Specificity

Expressed in the cerebral cortex of the brain and at higher levels in some astrocytic brain tumors such as astrocytomas, glioblastomas and primitive neuroectodermal tumors.

Subcellular Localizations

Membrane; Single-pass type I membrane protein. Cell membrane.

Diseases

Neoplasms
Cell Invasion
Malignant Neoplasm Of Breast
Trinucleotide Repeat Expansion
Schizophrenia
Glioblastoma
Oligodendroglioma
Pre-eclampsia
Brain Neoplasms
Carcinoma
Endoplasmic Reticulum Stress
Mental Disorders
Malignant Neoplasms

Neuroectodermal Tumors
Neuroectodermal Tumor, Primitive
Nervousness
Noninfiltrating Intraductal Carcinoma
Genetic Diseases, Inborn
Mammary Neoplasms
Medulloblastoma

Pathways

Cell Proliferation
Cell Growth
Pathogenesis

PTMs

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLITRK4

References

PMID: 14557068 by Aruga J., et al. Human SLITRK family genes: genomic organization and expression profiling in normal brain and brain tumor tissue.

PMID: 27812321 by Kang H., et al. Slitrk missense mutations associated with neuropsychiatric disorders distinctively impair Slitrk trafficking and synapse formation.