Anti-SLIT and NTRK-like protein 4 Slitrk4 Antibody

Product Name

Anti-SLIT and NTRK-like protein 4 Slitrk4 Antibody

View all SLITRK4 Antibodies

SKU/Catalog Number

A14468

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-SLIT and NTRK-like protein 4 Slitrk4 Antibody (Catalog # A14468). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Slitrk4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-SLIT and NTRK-like protein 4 Slitrk4 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A14468)

Host

Rabbit

Contents

Slitrk4 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Slitrk4 antibody was raised against a 14 amino acid synthetic peptide from near the amino terminus of human Slitrk4. The immunogen is located within amino acids 30 - 80 of Slitrk4.

Cross-reactivity

This antibody is predicted to have no cross-reactivity to other Slitrk proteins.

Reactive Species

A14468 is reactive to SLITRK4 in Human, Mouse, Rat

Observed Molecular Weight

68 kDa

Calculated molecular weight

94.3 kDa

Background of SLITRK4

SLIT and NTRK-like family 4 (Slitrk4) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family. Like every other Slitrk protein except Slitrk1, overexpression of Slitrk4 inhibited neurite outgrowth in cultured neurons, suggesting that these proteins are involved in the control of neurite outgrowth.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A14468 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Slitrk4 antibody can be used for detection of Slitrk4 by Western blot at 0.5 and 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

See full target information SLITRK4

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