Smc6 Antibodies

AND Smc6 ELISA kits, Smc6 Proteins

Many biological assays use antibodies to detect Smc6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Smc6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Smc6 antibodies...

We validate the specificity of these antibodies to Smc6 by testing them on tissues known to express Smc6 positively and negatively. Browse below to find the Smc6 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Smc6 Infographic by Boster Bio

All Smc6 Products

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Applications

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Anti-SMC6L1 Antibody Picoband®

1 Citations 4 Q&As

Western blot analysis of SMC6L1 using anti-SMC6L1 antibody (A01554-1)

IHC analysis of SMC6L1 using anti-SMC6L1 antibody (A01554-1)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, IHC-F, ICC, WB

$370
Cat # A01554-1
100 μg/vial

SMC6L1 (SMC6) (NM_024624) Human Recombinant Protein

Coomassie blue staining of purified SMC6 protein

$1249
Cat # PROTQ96SB8
20 µg

Anti-SMC6 Antibody Picoband®

Western blot analysis of SMC6 using anti-SMC6 antibody (A01554-2)

IHC analysis of SMC6 using anti-SMC6 antibody (A01554-2)

IF analysis of SMC6 and Tubulin beta using anti-SMC6 antibody (A01554-2) and anti-Tubulin beta antibody (M05613-4)

Human, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A01554-2
100 μg/vial

Smc6 Overview

Facts about Structural maintenance of chromosomes protein 6.

Structural maintenance of chromosomes protein 6 (Smc6)

Core part of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex might promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks.

The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components (By similarity). .

Gene Information

Mouse
Gene Name:	Smc6
Uniprot:	Q924W5
Entrez:	67241

Family

Belongs to:

SMC family

Alternative Names

FLJ22116; hSMC6; SMC protein 6; SMC6 structural maintenance of chromosomes 6-like 1 (yeast); SMC6 structural maintenance of chromosomes 6-like 1; SMC-6; SMC6L1FLJ35534; structural maintenance of chromosomes 6; structural maintenance of chromosomes protein 6

Molecular Weight

Mass (kDA):
127.198 kDA

Genomic Context


Mouse

Location:	12\|12 A1.1
Sequence:	12;

Diseases

Genomic Instability
Malignant Neoplasms
Neoplasms
Neuroblastoma
Genotoxic Stress
Disuse Muscle Atrophy
Chromosomal Duplication
Muscular Atrophy
Atrophy
Carcinogenesis
Telomere Shortening

Leukemia
Chromosome Breakage
Radiation Induced Dna Damage
Homogeneously Staining Region
Growth Arrest

Pathways

Dna Repair
Dna Replication
Cell Cycle
Sister Chromatid Cohesion
Mitosis
Chromosome Segregation
Chromosome Condensation
Recombinational Repair
Hypersensitivity
Cell Cycle Arrest
Anaphase
Interphase
Postreplication Repair

Localization
Senescence
S Phase
Chromosome Organization
Rna Interference
Brain Development
Proteolysis

PTMs

Sumoylation
Phosphorylation

Reduction
Oxidation

Ubiquitination

Research Areas

Cell Cycle and Replication
DNA Repair

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Smc6

References

PMID: 11408570 by Taylor E.M., et al. Characterization of a novel human SMC heterodimer homologous to the Schizosaccharomyces pombe Rad18/Spr18 complex.