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- Table of Contents
Facts about Sorbitol dehydrogenase.
May play a role in the sperm motility by providing an energetic source for sperm. .
Human | |
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Gene Name: | SORD |
Uniprot: | Q00796 |
Entrez: | 6652 |
Belongs to: |
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zinc-containing alcohol dehydrogenase family |
EC 1.1.1; EC 1.1.1.14; L-iditol 2-dehydrogenase; sorbitol dehydrogenase; SORD1
Mass (kDA):
38.325 kDA
Human | |
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Location: | 15q21.1 |
Sequence: | 15; NC_000015.10 (45023195..45077185) |
Expressed in kidney and epithelial cells of both benign and malignant prostate tissue. Expressed in epididymis (at protein level).
Mitochondrion membrane; Peripheral membrane protein. Cell projection, cilium, flagellum. Associated with mitochondria of the midpiece and near the plasma membrane in the principal piece of the flagellum. Also found in the epididymosome, secreted by the epididymal epithelium and that transfers proteins from the epididymal fluid to the sperm surface.
If you're working on a project related to DMD, Boster Bio's SORD markers are an excellent choice. These antibodies are sensitive and can be found in a variety biologically relevant matrices. These markers are both highly sensitive and easily accessible. In fact, they have been cited in more than 29,000 scientific papers! Learn more about how this marker can help your research project.
Single domain antibodies can be derived from camelids or engineered human cells. Antibodies from camelids are a more expensive option, but are useful for basic research. Boster Bio's antibodies have been cited in more than 29,000 scientific publications. The antibody library is widely used in many fields including immunology, cell biology, virology, and other areas.
Sanyou Biopharmaceuticals can make antibodies against SARS/CoV-2. SYZ001 (a human IgG) targets one epitope from the SARS/CoV-2 ROB. These two antibodies are very similar. However, SYZ001 is stronger against Epsilon than Delta. All anti-SARS-CoV-2 antibodies do not have the same Fc functionality. S2h23-S2M11 and S309 epitopes act as strong inducers of ADCC activation.
While there is much debate over the sensitivity SORD Markers, there are some consensus points that they are highly sensitive. They are useful for species identification. These markers can be used in vitro, in-silico, or in situ. These markers require high quality control and should only used in very specific applications. Sensitivity screening is crucial for these reasons. This article provides an overview on the current state of SORD Markers.
The results of studies involving newly designed SORD marks varied widely. Contrary to studies using ddPCR markers, 165 studies used brand-new markers. 26 of these reports included sensitivity screening to determine LoD markers. The remaining 139 studies failed to report the results. The patterns did not change over time. Additionally, 88 studies reported their marker LoD while 77 did not report this information. The data were also inconsistent across studies.
Multiple candidate markers can help identify sensitive genes in large groups. Different marker design platforms generate different high-score candidates. They may have different algorithms. Multiple candidate markers are identified. Sensitivity validation is done to ensure high accuracy. This method allows researchers the ability to identify low-LoD markers while maintaining high sensitivity. These markers need to be validated thoroughly. They must be highly specific in order to detect disease-causing organisms.
Laboratory and clinicians must be familiar with the current microbiological techniques to determine if a SORD Marker's sensitiveness. For accurate diagnosis of sepsis, and for goal-directed therapy for those suffering from it, it is crucial to develop sensitive biomarkers. However, despite their high-sensitivity, the results are mostly a matter of judgement. Ultimately, an accurate diagnosis and treatment will be possible.
Boster Bio has a variety SORD reagents available. They are available in a wide range biologically relevant matrixes, including a wide selection of human, mouse, bacterial samples. Boster Bio SORD markers allow you to analyze the effects RNA, DNA and mRNA on a wide range of biological processes. The company can provide the required custom services as well as BeNeLux orders.
PMID: 8088829 by Lee F.K., et al. The human sorbitol dehydrogenase gene: cDNA cloning, sequence determination, and mapping by fluorescence in situ hybridization.
PMID: 7782086 by Iwata T., et al. Structural organization of the human sorbitol dehydrogenase gene (SORD).