Sepiapterin reductase Antibodies

AND SPR ELISA kits, Sepiapterin reductase Proteins

Many biological assays use antibodies to detect Sepiapterin reductase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Sepiapterin reductase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Sepiapterin reductase antibodies...

We validate the specificity of these antibodies to Sepiapterin reductase by testing them on tissues known to express SPR positively and negatively. Browse below to find the SPR antibody that suites your experiment. We have 32 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for Sepiapterin reductase? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the SPR Western Blot Guide

SPR Infographic by Boster Bio

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Anti-Sprouty 4/Spry-4/SPRY4 Antibody Picoband®

1 Citations

Western blot analysis of Sprouty 4/Spry-4/SPRY4 using anti-Sprouty 4/Spry-4/SPRY4 antibody (A04343-2)

IHC analysis of Sprouty 4/Spry-4/SPRY4 using anti-Sprouty 4/Spry-4/SPRY4 antibody (A04343-2)

Human

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A04343-2
100 μg/vial

Anti-SPRED2 Antibody Picoband®

Western blot analysis of SPRED2 using anti-SPRED2 antibody (A06368-1)

IF analysis of SPRED2 using anti-SPRED2 antibody (A06368-1) and anti-Tubulin Alpha antibody (M03989-3)

Flow Cytometry analysis of HepG2 cells using anti-SPRED2 antibody (A06368-1)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A06368-1
100 µg/vial

Anti-SPRED1 Antibody Picoband®

Western blot analysis of SPRED1 using anti-SPRED1 antibody (A03613-1)

IF analysis of SPRED1 using anti-SPRED1 antibody (A03613-1)

Flow Cytometry analysis of HEL cells using anti-SPRED1 antibody (A03613-1)

Human

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A03613-1
100 μg/vial

Anti-SPR Antibody Picoband®

1 Citations

Western blot analysis of SPR using anti-SPR antibody (A00416-1)

Human, Mouse

ELISA, WB

$370
Cat # A00416-1
100 μg/vial

Anti-Spry-2/SPRY2 Antibody Picoband®

Western blot analysis of Spry-2/SPRY2 using anti-Spry-2/SPRY2 antibody (A02089-2)

Flow Cytometry analysis of U87 cells using anti-Spry-2/SPRY2 antibody (A02089-2)

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A02089-2
100 μg/vial

Anti-Matriptase 2/TMPRSS6 Antibody Picoband®

Western blot analysis of Matriptase 2/TMPRSS6 using anti-Matriptase 2/TMPRSS6 antibody (A02093-1)

Flow Cytometry analysis of MCF-7 cells using anti-Matriptase 2/TMPRSS6 antibody (A02093-1)

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A02093-1
100 μg/vial

Anti-Sprouty 4 Rabbit Monoclonal Antibody

Western blot analysis of Sprouty 4 expression in MCF7 cell lysate

Human, Mouse, Rat

Flow Cytometry, IP, IF, ICC, WB

$370
Cat # M04343
100 μl/vial

Anti-SPRYD3 Antibody

Western blot analysis of SPRYD3 in human brain tissue lysate with SPRYD3 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide

Immunohistochemistry of SPRYD3 in mouse brain tissue with SPRYD3 antibody at 5 μg/mL

Immunofluorescence of SPRYD3 in mouse brain tissue with SPRYD3 antibody at 20 μg/mL

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$481
Cat # A19152
0.1 mg

Anti-Spred3 Antibody

Western blot analysis of Spred3 in mouse brain tissue lysate with Spred3 antibody at (A) 2 and (B) 4 μg/mL

Human

ELISA, IF, IHC-P, WB

$481
Cat # A15231
0.1 mg

Anti-SPRYD5 TRIM51 Antibody

Western blot analysis of SPRYD5 in rat brain tissue lysate with SPRYD5 antibody at (A) 0

Immunohistochemistry of SPRYD5 in mouse brain tissue with SPRYD5 antibody at 5 μg/mL

Immunofluorescence of SPRYD5 in mouse brain tissue with SPRYD5 antibody at 20 μg/mL

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$481
Cat # A15117
0.1 mg

SPRED3 (NM_001042522) Human Over-expression Lysate

SPRED3 Human Over-expression Lysates NM_001039616

Human

$628
Cat # LS399473
20 µg, 100 µg

SPRED2 (NM_181784) Human Over-expression Lysate

SPRED2 Human Over-expression Lysates NM_001128210

Human

$960
Cat # LS200734
20 µg, 100 µg

Anti-Spred1 Antibody

Western blot analysis of Spred1 in mouse brain tissue lysate with Spred1 antibody at (A) 1 and (B) 2 μg/mL

Immunohistochemistry of Spred1 in human brain tissue with Spred1 antibody at 2

Human, Mouse, Rat

ELISA, IHC-P, WB

$481
Cat # A03613
0.1 mg

Sprouty 1 (SPRY1) (NM_005841) Human Over-expression Lysate

Sprouty 1 (SPRY1) Human Over-expression Lysates NM_005841

Human

$628
Cat # LS010252
20 µg, 100 µg

SPR (NM_003124) Human Over-expression Lysate

Human

$628
Cat # LS006697
20 µg, 100 µg

SPRR4 (NM_173080) Human Over-expression Lysate

Human

$628
Cat # LS163778
20 µg, 100 µg

SPRED1 (NM_152594) Human Over-expression Lysate

Human

$960
Cat # LS161742
20 µg, 100 µg

SPRYD3 (NM_032840) Human Over-expression Lysate

Human

$960
Cat # LS084926
20 µg, 100 µg

Sprouty 4 (SPRY4) (NM_030964) Human Over-expression Lysate

Human

$628
Cat # LS081848
20 µg, 100 µg

Sprouty 2 (SPRY2) (NM_005842) Human Over-expression Lysate

Human

$628
Cat # LS010253
20 µg, 100 µg

Anti-Spred2 Antibody

Human

ELISA, WB

$481
Cat # A06368
0.1 mg

SPRYD5 (TRIM51) (NM_032681) Human Over-expression Lysate

Human

$628
Cat # LS084767
20 µg, 100 µg

Sprouty 3 (SPRY3) (NM_005840) Human Over-expression Lysate

Human

$628
Cat # LS010251
20 µg, 100 µg

Anti-SPRR4 Antibody

Human

ELISA, IHC

$370
Cat # A16019
100 μg/vial

Anti-Sprouty 2 SPRY2 Monoclonal Antibody

All lanes use the Antibody at 1:3K dilution for 1 hour at room temperature

Human, Rat

IP, IF, IHC, ICC, WB

$370
Cat # M02089
100 μl

Mouse Spr Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ91XH5
Starting from 20ug

Human Sepiapterin reductase Recombinant Protein

SDS-PAGE

$250
Cat # PROTP35270
Starting from 20ug

Human SPRY4 Recombinant Protein

SDS-PAGE, Denatured

$250
Cat # PROTQ9C004
Starting from 20ug

SPRR4 (NM_173080) Human Recombinant Protein

Coomassie blue staining of purified SPRR4 protein

$1249
Cat # PROTQ96PI1
20 µg

SPRYD3 (NM_032840) Human Recombinant Protein

Coomassie blue staining of purified SPRYD3 protein

$1249
Cat # PROTQ8NCJ5
20 µg

Human SPRED1 Recombinant Protein

SDS-PAGE, Denatured

$275
Cat # PROTQ7Z699
Starting from 10ug

SPRED3 (NM_001039616) Human Recombinant Protein

Coomassie blue staining of purified SPRED3 protein

$1249
Cat # PROTQ2MJR0
20 µg

SPR Overview

Facts about Sepiapterin reductase.

SPR 3D structure. Source: alphafold

Sepiapterin reductase (SPR)

Catalyzes the last one or two reductions in tetra- hydrobiopterin biosynthesis to form 5,6,7,8-tetrahydrobiopterin. .

Gene Information

Human
Gene Name:	SPR
Uniprot:	P35270
Entrez:	6697

Family

Belongs to:

sepiapterin reductase family

Alternative Names

EC 1.1.1.153; Gm10328; SDR38C1; sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase); sepiapterin reductase; short chain dehydrogenase/reductase family 38C, member 1; SPR

Molecular Weight

Mass (kDA):
28.048 kDA

Genomic Context


Human

Location:	2p13.2
Sequence:	2; NC_000002.12 (72887408..72892158)

Subcellular Localizations

Cytoplasm.

Diseases

Malignant Neoplasms
Tissue Adhesions
Neoplasms
Malaria
Hiv Infections
Inflammation
Pain
Alzheimer's Disease
Diabetes Mellitus
Infective Disorder
Influenza
Carcinoma
Cerebral Palsy

Muscle Spasticity
Salmonella Infections
Malaria, Falciparum
Headache
Nervousness
Hepatitis
Hypertensive Disease

Pathways

Regeneration
Transport
Localization
Cell Adhesion
Immune Response
Coagulation
Cell Proliferation
Translation
Pathogenesis
Conjugation
Secretion
Glycosylation
Angiogenesis

Proteolysis
Cell Growth
Virulence
Reflex
Methylation
Blood Coagulation
Cell Cycle

PTMs

Biotinylation
Phosphorylation
Cleavage
Glycosylation
Methylation
Oxidation
Reduction
Carboxylation
Dephosphorylation
Amination

Nitration
Myristoylation
Sumoylation
Glutathionylation
Hydroxylation
Deamination
Amidation
Sulphation
Phosphorothioation
Bromination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SPR

References

PMID: 1883349 by Ichinose H., et al. Cloning and sequencing of cDNA encoding human sepiapterin reductase -- an enzyme involved in tetrahydrobiopterin biosynthesis.

PMID: 8440319 by Maier J., et al. Detection of a novel sepiapterin reductase mRNA: assay of mRNA in various cells and tissues of various species.

1 Publications of Boster Sepiapterin reductase Antibodies & ELISA Kits

PubMed ID: 24596465, Alterations in the endometrium of rats, rabbits, and?Macaca mulatta?that receive...

*More publications can be found for each product on its corresponding product page