Protein sprouty homolog 2 Antibodies

AND SPRY2 ELISA kits, Protein sprouty homolog 2 Proteins

Many biological assays use antibodies to detect Protein sprouty homolog 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein sprouty homolog 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein sprouty homolog 2 antibodies...

We validate the specificity of these antibodies to Protein sprouty homolog 2 by testing them on tissues known to express SPRY2 positively and negatively. Browse below to find the SPRY2 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for Protein sprouty homolog 2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the SPRY2 Western Blot Guide

SPRY2 Infographic by Boster Bio

All SPRY2 Products

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Applications

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Anti-Spry-2/SPRY2 Antibody Picoband®

Western blot analysis of Spry-2/SPRY2 using anti-Spry-2/SPRY2 antibody (A02089-2)

Flow Cytometry analysis of U87 cells using anti-Spry-2/SPRY2 antibody (A02089-2)

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A02089-2
100 μg/vial

Anti-Matriptase 2/TMPRSS6 Antibody Picoband®

Western blot analysis of Matriptase 2/TMPRSS6 using anti-Matriptase 2/TMPRSS6 antibody (A02093-1)

Flow Cytometry analysis of MCF-7 cells using anti-Matriptase 2/TMPRSS6 antibody (A02093-1)

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A02093-1
100 μg/vial

Sprouty 2 (SPRY2) (NM_005842) Human Over-expression Lysate

Human

$628
Cat # LS010253
20 µg, 100 µg

Anti-Sprouty 2 SPRY2 Monoclonal Antibody

All lanes use the Antibody at 1:3K dilution for 1 hour at room temperature

Human, Rat

IP, IF, IHC, ICC, WB

$370
Cat # M02089
100 μl

SPRY2 Overview

Facts about Protein sprouty homolog 2.

SPRY2 3D structure. Source: alphafold

Protein sprouty homolog 2 (SPRY2)

May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis. .

Gene Information

Human
Gene Name:	SPRY2
Uniprot:	O43597
Entrez:	10253

Family

Belongs to:

sprouty family

Alternative Names

hSPRY2; MGC23039; protein sprouty homolog 2; sprouty (Drosophila) homolog 2; sprouty 2; sprouty homolog 2 (Drosophila); SPRY2; spry-2

Molecular Weight

Mass (kDA):
34.688 kDA

Genomic Context


Human

Location:	13q31.1
Sequence:	13; NC_000013.11 (80335976..80341126, complement)

Subcellular Localizations

Cytoplasm, cytoskeleton. Cell projection, ruffle membrane. Associated with microtubules in unstimulated cells but is translocated to the membrane ruffles in cells stimulated ith EGF (epidermal growth factor).

Diseases

Neoplasms
Malignant Neoplasms
Cell Transformation, Neoplastic
Carcinoma
Cell Invasion
Malignant Paraganglionic Neoplasm
Tumor Angiogenesis
Liver Carcinoma
Malignant Tumor Of Colon
Colonic Neoplasms
Adenocarcinoma
Carcinogenesis
Hyperplasia

Liver Neoplasms
Melanoma
Hypoxia
Lung Neoplasms
Lymphoma
Tissue Adhesions
Prostatic Neoplasms

Pathways

Cell Proliferation
Cell Migration
Cell Growth
Lung Development
Angiogenesis
Cell Death
Localization
Pathogenesis
Endocytosis
Methylation
Regeneration
Cell Cycle
Lung Morphogenesis

Lung Growth
Secretion
Cell Adhesion
Cell Differentiation
Oocyte Maturation
Reverse Transcription
Muscle Cell Proliferation

PTMs

Phosphorylation
Ubiquitination
Methylation
Dephosphorylation

Cleavage
Nitrosylation
Hydroxylation
Palmitoylation

Research Areas

Growth and Development
Neuronal Cell Markers
Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SPRY2

References

PMID: 9458049 by Hacohen N., et al. Sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways.

PMID: 10887178 by Lim J., et al. Sprouty proteins are targeted to membrane ruffles upon growth factor receptor tyrosine kinase activation. Identification of a novel translocation domain.