SPTBN4 Antibodies

AND SPTBN4 ELISA kits, SPTBN4 Proteins

Many biological assays use antibodies to detect SPTBN4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SPTBN4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SPTBN4 antibodies...

We validate the specificity of these antibodies to SPTBN4 by testing them on tissues known to express SPTBN4 positively and negatively. Browse below to find the SPTBN4 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for SPTBN4? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the SPTBN4 IHC Guide

SPTBN4 Infographic by Boster Bio

All SPTBN4 Products

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Anti-SPTN4 SPTBN4 Antibody

Human

IF, IHC

$380
Cat # A14322
100ul

SPTBN4 Overview

Facts about Spectrin beta chain, non-erythrocytic 4.

SPTBN4 3D structure. Source: alphafold

Spectrin beta chain, non-erythrocytic 4 (SPTBN4)

Gene Information

Human
Gene Name:	SPTBN4
Uniprot:	Q9H254
Entrez:	57731

Family

Belongs to:

spectrin family

Alternative Names

beta-IV spectrin; KIAA1642; QV; spectrin beta chain, brain 3; spectrin, beta, non-erythrocytic 4; spectrin, non-erythroid beta chain 3; SPNB4; SPTBN3

Molecular Weight

Mass (kDA):
288.985 kDA

Genomic Context


Human

Location:	19q13.2
Sequence:	19; NC_000019.10 (40467001..40576464)

Tissue Specificity

Expressed in skeletal muscle at the sarcolemma and in the muscle capillaries (at protein level) (PubMed:28540413). Abundantly expressed in brain and pancreatic islets (PubMed:11086001).

Subcellular Localizations

Cytoplasm, cytoskeleton. Cytoplasm, cell cortex.

Interacting Proteins

DISC1
PTPRN

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SPTBN4

References

PMID: 11294830 by Tse W.T., et al. A new spectrin, beta-IV, has a major truncated isoform that associates with promyelocytic leukemia protein nuclear bodies and the nuclear matrix.

PMID: 11086001 by Berghs S., et al. BetaIV spectrin, a new spectrin localized at axon initial segments and nodes of Ranvier in the central and peripheral nervous system.