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- Table of Contents
Sorcin Antibodies
AND SRI ELISA kits, Sorcin Proteins
Many biological assays use antibodies to detect Sorcin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Sorcin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Sorcin antibodies...
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SRI Infographic by Boster Bio
All SRI Products
Product
Figures
Specificity
Applications
Price
Anti-SRI Antibody Picoband®
4 Q&As
Human, Mouse, Rat
Flow Cytometry, IF, IHC, IHC-F, ICC, WB
$370
Cat # A00222
100 μg/vial
Cat # A00222
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A00222-2
100 μg/vial
Cat # A00222-2
100 μg/vial
SRI Overview
Facts about Sorcin.
Sorcin (SRI)
Calcium-binding protein that modulates excitation- contraction coupling in the heart. Contributes to calcium homeostasis in the heart sarcoplasmic reticulum.
Modulates the activity of RYR2 calcium channels. .
Gene Information
| Human | |
|---|---|
| Gene Name: | SRI |
| Uniprot: | P30626 |
| Entrez: | 6717 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
calcium binding protein amplified in mutlidrug-resistant cells; CP22; CP-22; FLJ26259,22 kDa protein; H_RG167B05.1; SCN; sorcin; V19
Molecular Weight
Mass (kDA):
21.676 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 7q21.12 |
| Sequence: | 7; NC_000007.14 (88205115..88226993, complement) |
Tissue Specificity
Detected in cardiac myocytes.
Subcellular Localizations
Cytoplasm. Sarcoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Relocates to the sarcoplasmic reticulum membrane in response to elevated calcium levels.
Diseases
- Obsessive-compulsive Disorder
- Osteochondritis Dissecans
- Depressive Disorder
- Corneal Diseases
- Anxiety Disorders
- Neoplasms
- Malignant Neoplasms
- Major Depressive Disorder
- Mental Disorders
- Infarction
- Myocardial Infarction
- Hypertensive Disease
Interacting Proteins
- ANXA7
- CALCOCO2
- PRR13
- STAT3
- TCF12
Pathways
- Phototaxis
- Transport
- Platelet Aggregation
- Pathogenesis
- Localization
- Drug Resistance
- Negative Phototaxis
- Chemotaxis
- Vasoconstriction
- Proton Transport
- Methylation
- Secretion
- Positive Phototaxis
PTMs
- Phosphorylation
- Methylation
- Cleavage
- Demethylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SRI
bosterbio.com/bosterbio-gene-info-cards/SRI
References
PMID: 7873602 by Wang S.L., et al. Isolation and molecular cloning of human sorcin a calcium-binding protein in vincristine-resistant HOB1 lymphoma cells.
PMID: 8561500 by Lee W.P.; Purification, cDNA cloning, and expression of human sorcin in vincristine-resistant HOB1 lymphoma cell lines.