SRPX2 Antibodies

AND SRPX2 ELISA kits, SRPX2 Proteins

Many biological assays use antibodies to detect SRPX2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SRPX2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SRPX2 antibodies...

We validate the specificity of these antibodies to SRPX2 by testing them on tissues known to express SRPX2 positively and negatively. Browse below to find the SRPX2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for SRPX2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the SRPX2 IHC Guide

SRPX2 Infographic by Boster Bio

All SRPX2 Products

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Applications

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Anti-SRPX2 Antibody

Western blot analysis of SRPX2 in human lung tissue lysate with SRPX2 antibody at (A) 1 and (B) 2 μg/mL

Immunohistochemistry of SRPX2 in rat lung tissue with SRPX2 antibody at 5 μg/mL

Immunofluorescence of SRPX2 in human lung tissue with SRPX2 antibody at 20 μg/mL

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$481
Cat # A06268
0.1 mg

SRPX2 (NM_014467) Human Over-expression Lysate

Human

$628
Cat # LS027286
20 µg, 100 µg

SRPX2 Overview

Facts about Sushi repeat-containing protein SRPX2.

SRPX2 3D structure. Source: alphafold

Sushi repeat-containing protein SRPX2 (SRPX2)

Plays a role in angiogenesis by inducing endothelial cell migration and the formation of vascular network (strings ). Involved in cellular migration and adhesion.

Increases the phosphorylation levels of FAK. Interacts with and increases the mitogenic action of HGF.

Gene Information

Human
Gene Name:	SRPX2
Uniprot:	O60687
Entrez:	27286

Family

Belongs to:

No superfamily

Alternative Names

BPP; CBPS; RESDX; SRPULPMGX; sushi repeat-containing protein SRPX2; sushi-repeat containing protein, X-linked 2; sushi-repeat protein up-regulated in leukemia; sushi-repeat-containing protein, X-linked 2

Molecular Weight

Mass (kDA):
52.972 kDA

Genomic Context


Human

Location:	Xq22.1
Sequence:	X; NC_000023.11 (100644199..100675788)

Tissue Specificity

Expressed in neurons of the rolandic area of the brain (at protein level). Highly expressed in the brain, placenta, lung, trachea, uterus, adrenal gland, heart, ovary and placenta. Weakly expressed in the peripheral blood, brain and bone marrow. Expressed in numerous cancer cell lines and in gastrointestinal cancer cells. Higher levels found in colorectal cancers than in normal colonic mucosa.

Subcellular Localizations

Secreted. Cytoplasm. Cell surface. Cell junction, synapse.

Diseases

Epilepsy
Polymicrogyria
Tissue Adhesions
Epilepsy, Rolandic
Ectopic Tissue
Apraxias
Language Disorders
Dysplasia
Cortical Dysplasia
Subcortical Band Heterotopia
Apraxia, Developmental Verbal

Verbal Dyspraxia
Lissencephaly
Epilepsies, Partial
Malformations Of Cortical Development
Nervousness

Pathways

Plasminogen Activation
Cognition
Cell Adhesion
Brain Development
Proteolysis
Localization
Angiogenesis
Blood Coagulation
Endochondral Ossification
Cell Proliferation
Cell Migration
Receptor Clustering

Tube Formation
Ossification
Chondrocyte Differentiation
Cartilage Development
Endothelial Cell Migration
System Development
Coagulation

PTMs

Phosphorylation

Ribosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SRPX2

References

PMID: 9864177 by Kurosawa H., et al. Two candidate downstream target genes for E2A-HLF.

PMID: 16497722 by Roll P., et al. SRPX2 mutations in disorders of language cortex and cognition.