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Product Info Summary
| SKU: | A06268 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-SRPX2 Antibody
SKU/Catalog Number
A06268
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-SRPX2 Antibody (Catalog # A06268). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-SRPX2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06268)
Host
Rabbit
Contents
SRPX2 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
SRPX2 antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human SRPX2. The immunogen is located within the first 50 amino acids of SRPX2.
Reactive Species
A06268 is reactive to SRPX2 in Human, Mouse, Rat
Observed Molecular Weight
68 kDa
Calculated molecular weight
53.0 kDa
Background of SRPX2
Sushi-repeat-containing protein X-linked 2 (SRPX2) is a neural gene functioning in the speech and language center of the human brain; mutations in this gene lead to epilepsy, speech dyspraxia, mental retardation and cognitive disorders. Recently, SRPX2 was found to be a novel mediator of angiogenesis and can act as a ligand for the urokinase-type plasminogen activator, a protein that can facilitate invasive migration of sprouting endothelial cells. SRPX2 is also overexpressed in gastric cancer, leading to increased phosphorylation levels of focal adhesion kinase and enhanced cellular migration and adhesion, suggesting that SRPX2 may be a potential target in the treatment of metastatic cancers.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A06268 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
SRPX2 antibody can be used for detection of SRPX2 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in rat samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of SRPX2 in human lung tissue lysate with SRPX2 antibody at (A) 1 and (B) 2 μg/mL.
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Immunohistochemistry of SRPX2 in rat lung tissue with SRPX2 antibody at 5 μg/mL.
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Immunofluorescence of SRPX2 in human lung tissue with SRPX2 antibody at 20 μg/mL.
Specific Publications For Anti-SRPX2 Antibody (A06268)
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