ST3GAL6 Antibodies

AND ST3GAL6 ELISA kits, ST3GAL6 Proteins

Many biological assays use antibodies to detect ST3GAL6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ST3GAL6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ST3GAL6 antibodies...

We validate the specificity of these antibodies to ST3GAL6 by testing them on tissues known to express ST3GAL6 positively and negatively. Browse below to find the ST3GAL6 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ST3GAL6 Infographic by Boster Bio

All ST3GAL6 Products

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Anti-ST3gal6 Antibody

Western blot analysis of ST3gal6 in HeLa cell lysate with ST3gal6 antibody at (A) 1 and (B) 2 μg/mL

Immunocytochemistry of ST3gal6 in HeLa cells with ST3gal6 antibody at 5 μg/mL

Human, Mouse, Rat

ELISA, ICC, WB

$481
Cat # A09513
0.1 mg

ST3GAL6 (NM_006100) Human Recombinant Protein

Coomassie blue staining of purified ST3GAL6 protein

$1249
Cat # PROTQ9Y274
20 µg

ST3GAL6 (NM_006100) Human Over-expression Lysate

Human

$628
Cat # LS010402
20 µg, 100 µg

ST3GAL6 Overview

Facts about Type 2 lactosamine alpha-2,3-sialyltransferase.

ST3GAL6 3D structure. Source: alphafold

Type 2 lactosamine alpha-2,3-sialyltransferase (ST3GAL6)

Involved in the synthesis of sialyl-paragloboside, a precursor of sialyl-Lewis X determinant. Has a alpha-2,3- sialyltransferase activity toward Gal-beta1,4-GlcNAc structure on glycoproteins and glycolipids.

Has a restricted substrate specificity, it uses Gal-beta1,4-GlcNAc on glycoproteins, and neolactotetraosylceramide and neolactohexaosylceramide, but not lactotetraosylceramide, lactosylceramide or asialo-GM1. .

Gene Information

Human
Gene Name:	ST3GAL6
Uniprot:	Q9Y274
Entrez:	10402

Family

Belongs to:

glycosyltransferase 29 family

Alternative Names

alpha2,3-sialyltransferase; CMP-NeuAc:beta-galactoside alpha-2,3-sialyltransferase VI; EC 2.4.99; EC 2.4.99.-; EC 2.4.99.9; Sialyltransferase 10; SIAT10; ST3 beta-galactoside alpha-2,3-sialyltransferase 6; ST3Gal VI; ST3GAL6; ST3GALVI; ST3GALVIsialyltransferase 10 (alpha-2,3-sialyltransferase VI); type 2 lactosamine alpha-2,3-sialyltransferase

Molecular Weight

Mass (kDA):
38.214 kDA

Genomic Context


Human

Location:	3q12.1
Sequence:	3; NC_000003.12 (98732236..98795845)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Golgi apparatus membrane; Single-pass type II membrane protein.

Diseases

Carcinoma
Malignant Neoplasms
Neoplasms
Malignant Paraganglionic Neoplasm
Cystic Fibrosis
Neoplasm Metastasis
Embryonal Carcinoma
Malignant Neoplasm Of Breast
Gastrointestinal Neoplasms
Fibrosis
Neoplasms, Hormone-dependent
Lupus Erythematosus, Systemic
Mammary Neoplasms

Colorectal Cancer
Malignant Neoplasm Of Gastrointestinal Tract
Epstein-barr Virus Infections
Liver Carcinoma
Tissue Adhesions
Mental Disorders
Decreased Interest

Pathways

Glycosylation
Sulfation
Transport
Methylation
Secretory Pathway
Dna Hypermethylation

PTMs

Glycosylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ST3GAL6

References

PMID: 10206952 by Okajima T., et al. Molecular cloning of a novel alpha2,3-sialyltransferase (ST3Gal VI) that sialylates type II lactosamine structures on glycoproteins and glycolipids.