STAM-binding protein Antibodies

AND STAMBP ELISA kits, STAM-binding protein Proteins

Many biological assays use antibodies to detect STAM-binding protein, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with STAM-binding protein in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop STAM-binding protein antibodies...

We validate the specificity of these antibodies to STAM-binding protein by testing them on tissues known to express STAMBP positively and negatively. Browse below to find the STAMBP antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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STAMBP Infographic by Boster Bio

All STAMBP Products

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Specificity

Applications

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Anti-STAM-binding protein STAMBP Antibody

Western blot analysis of extracts of various cell lines, using STAMBP antibody at 1:1000 dilution

Immunofluorescence analysis of U2OS cells using STAMBP antibody

Immunohistochemistry of paraffin-embedded rat spleen using STAMBP antibody at dilution of 1:100

Human, Mouse, Rat

IP, IF, IHC, ICC, WB

$405
Cat # A05964
100ul

AMSH (STAMBP) (NM_201647) Human Recombinant Protein

Coomassie blue staining of purified STAMBP protein

$1062
Cat # PROTO95630
20 µg

Anti-AMSH Rabbit Monoclonal Antibody

Western blot analysis of AMSH expression in HeLa cell lysate

Human

$370
Cat # M05964
100 μl/vial

AMSH (STAMBP) (NM_006463) Human Over-expression Lysate

AMSH (STAMBP) Human Over-expression Lysates NM_006463

Human

$628
Cat # LS010617
20 µg, 100 µg

Anti-STAMBP Antibody Picoband®

Western blot analysis of STAMBP using anti-STAMBP antibody (A05964-1)

IHC analysis of STAMBP using anti-STAMBP antibody (A05964-1)

Human, Monkey, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A05964-1
100 μg/vial

STAMBP Overview

Facts about STAM-binding protein.

STAMBP 3D structure. Source: alphafold

STAM-binding protein (STAMBP)

Doesn't cleave'Lys-48'-linked polyubiquitin chains (By similarity). Plays a role in signal transduction for cell growth and MYC induction mediated by IL-2 and GM-CSF.

Potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory activity of SMAD6 and SMAD7. Has a key role in regulation of cell surface receptor-mediated endocytosis and ubiquitin-dependent sorting of receptors to lysosomes.

Gene Information

Human
Gene Name:	STAMBP
Uniprot:	O95630
Entrez:	10617

Family

Belongs to:

peptidase M67C family

Alternative Names

AMSH; AMSHAssociated molecule with the SH3 domain of STAM; EC 3.1.2.15; EC 3.4.19.-; Endosome-associated ubiquitin isopeptidase; MGC126516; MGC126518; STAM binding protein; STAM-binding protein; STAMBP

Molecular Weight

Mass (kDA):
48.077 kDA

Genomic Context


Human

Location:	2p13.1
Sequence:	2; NC_000002.12 (73828911..73873656)

Tissue Specificity

Ubiquitously expressed.

Subcellular Localizations

Nucleus. Membrane; Peripheral membrane protein. Cytoplasm. Early endosome.

Diseases

Cell Transformation, Neoplastic
Cerebral Atrophy
Nerve Degeneration
Neurodegenerative Disorders
Malignant Neoplasm Of Breast
Atrophy
Myeloproliferative Disease
Sequelae Aspects
Infertility
Growth Retardation

Metabolic Diseases
Malignant Neoplasms
Nervousness
Hiv Infections
Leukemia

Interacting Proteins

CHMP1A
CHMP1B
CHMP3
CHMP4B
CHMP5

GRAP2
GRB2
RNF11
STAM
STAM2

Pathways

Transport
Endocytosis
Localization
Cytokinesis
Protein Phosphorylation
Cell Proliferation
Cellular Homeostasis
Intracellular Signal Transduction
Oocyte Maturation
Conjugation
Cell Cycle

Cell Growth
Peptide Secretion
Regulation Of Cytokinesis
Rna Interference
Secretion
Oncogenesis

PTMs

Ubiquitination

Cleavage

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/STAMBP

References

PMID: 10383417 by Tanaka N., et al. Possible involvement of a novel STAM-associated molecule 'AMSH' in intracellular signal transduction mediated by cytokines.

PMID: 19906316 by Wang P., et al. Discovery of novel human transcript variants by analysis of intronic single-block EST with polyadenylation site.