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- Table of Contents
Facts about Syntaxin-4.
Together with STXB3 and VAMP2, may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes (By similarity). May also play a role in docking of synaptic vesicles at presynaptic active zones.
Human | |
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Gene Name: | STX4 |
Uniprot: | Q12846 |
Entrez: | 6810 |
Belongs to: |
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syntaxin family |
NY-REN-31; p35-2; Renal carcinoma antigen NY-REN-31; STX4; STX4Ap35-2; Syntaxin 4; syntaxin 4A (placental); syntaxin-4
Mass (kDA):
34.18 kDA
Human | |
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Location: | 16p11.2 |
Sequence: | 16; NC_000016.10 (31033095..31040168) |
Expressed in neutrophils and neutrophil- differentiated HL-60 cells. Expression in neutrophils increases with differentiation.
Cell membrane; Single-pass type IV membrane protein.
PMID: 8206394 by Li H., et al. Isolation and sequence analysis of the human syntaxin-encoding gene.
PMID: 8760387 by Jagadish M.N., et al. Insulin-responsive tissues contain the core complex protein SNAP-25 (synaptosomal-associated protein 25) A and B isoforms in addition to syntaxin 4 and synaptobrevins 1 and 2.