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- Table of Contents
SUCLG1 Antibodies
AND SUCLG1 ELISA kits, SUCLG1 Proteins
Many biological assays use antibodies to detect SUCLG1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SUCLG1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SUCLG1 antibodies...
Designing a Western blot for SUCLG1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the SUCLG1 Western Blot GuideDesigning an IHC experiment for SUCLG1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the SUCLG1 IHC GuideSUCLG1 Infographic by Boster Bio
All SUCLG1 Products
Product
Figures
Specificity
Applications
Price
Human, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A06274-1
100 µg/vial
Cat # A06274-1
100 µg/vial
SUCLG1 Overview
Facts about Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial.
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial (SUCLG1)
Succinyl-CoA synthetase functions from the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP or GTP and so represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of this enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for ATP or GTP is supplied by different beta subunits.
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Gene Information
| Human | |
|---|---|
| Gene Name: | SUCLG1 |
| Uniprot: | P53597 |
| Entrez: | 8802 |
Family
| Belongs to: |
|---|
| succinate/malate CoA ligase alpha subunit family |
Alternative Names
EC 6.2.1; EC 6.2.1.4; FLJ21114; FLJ43513; GALPHA; MTDPS9; SCS-alpha; succinate-CoA ligase, alpha subunit; succinate-CoA ligase, GDP-forming, alpha subunit; succinyl-CoA ligase [GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase subunit alpha; SUCLA1
Molecular Weight
Mass (kDA):
36.25 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2p11.2 |
| Sequence: | 2; NC_000002.12 (84423528..84459280, complement) |
Subcellular Localizations
Mitochondrion.
Diseases
- Mitochondrial Dna Depletion
- Mitochondrial Diseases
- Acidosis
- Acidosis, Lactic
- Methylmalonic Acidemia
- Mitochondrial Encephalomyopathies
- Mitochondrial Respiratory Chain Deficiencies
- Muscle Hypotonia
- Dysmyelopoietic Syndromes
- Leigh Disease
- Fetal Growth Retardation
Pathways
- Translation
- Oxidative Phosphorylation
- Pathogenesis
- Excretion
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SUCLG1
bosterbio.com/bosterbio-gene-info-cards/SUCLG1
References
PMID: 9128182 by James M., et al. The molecular basis for cross-reaction anti-dystrophin antibody with alpha-actinin.
PMID: 17668387 by Ostergaard E., et al. Deficiency of the alpha subunit of succinate-coenzyme A ligase causes fatal infantile lactic acidosis with mitochondrial DNA depletion.