SUCLG2 Antibodies

AND SUCLG2 ELISA kits, SUCLG2 Proteins

Many biological assays use antibodies to detect SUCLG2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SUCLG2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SUCLG2 antibodies...

We validate the specificity of these antibodies to SUCLG2 by testing them on tissues known to express SUCLG2 positively and negatively. Browse below to find the SUCLG2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for SUCLG2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the SUCLG2 IHC Guide

SUCLG2 Infographic by Boster Bio

All SUCLG2 Products

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Applications

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Anti-SUCLG2 Antibody Picoband®

Western blot analysis of SUCLG2 using anti-SUCLG2 antibody (A08268-1)

IHC analysis of SUCLG2 using anti-SUCLG2 antibody (A08268-1)

+12

Human, Mouse, Rat

ELISA, Flow Cytometry, IP, IF, IHC, ICC, WB

$370
Cat # A08268-1
100 µg/vial

SUCLG2 (NM_001177599) Human Over-expression Lysate

SUCLG2 Human Over-expression Lysates NM_001177599

Human

$628
Cat # LS008801
20 µg, 100 µg

SUCLG2 Overview

Facts about Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial.

SUCLG2 3D structure. Source: alphafold

Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial (SUCLG2)

GTP-specific succinyl-CoA synthetase works from the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA into the synthesis of GTP and so represents the only step of substrate-level phosphorylation in the TCA. The beta subunit offers nucleotide specificity of this enzyme and binds the substrate succinate, whereas the binding sites for coenzyme A and phosphate are found in the alpha subunit.

Gene Information

Human
Gene Name:	SUCLG2
Uniprot:	Q96I99
Entrez:	8801

Family

Belongs to:

succinate/malate CoA ligase beta subunit family

Alternative Names

EC 6.2.1; EC 6.2.1.4; GBETA; GTP-specific succinyl-CoA synthetase subunit beta; mitochondrial; succinate-CoA ligase, GDP-forming, beta subunit; succinyl-CoA ligase, GDP-forming, beta chain, mitochondrial; succinyl-CoA synthetase, beta-G chain

Molecular Weight

Mass (kDA):
46.511 kDA

Genomic Context


Human

Location:	3p14.1
Sequence:	3; NC_000003.12 (67360460..67654614, complement)

Tissue Specificity

Mainly expressed in liver, kidney, heart, spleen and skeletal muscle. Also found in intestine and colon, and in low amounts in lung, brain, prostate, testis and ovary.

Subcellular Localizations

Mitochondrion.

Diseases

Mitochondrial Dna Depletion
Acidosis
Complete Hearing Loss
Fracture
Obesity
Inborn Errors Of Metabolism
Acidosis, Lactic

Methylmalonic Acidemia
Muscle Hypotonia

Interacting Proteins

HSCB

Pathways

Cell Proliferation
Translation
Bone Development
Excretion

PTMs

Acetylation

Phosphoprotein

Research Areas

Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SUCLG2

References

PMID: 9765291 by Johnson J.D., et al. Genetic evidence for the expression of ATP- and GTP-specific succinyl-CoA synthetases in multicellular eucaryotes.