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Synaptotagmin-11 Antibodies
AND SYT11 ELISA kits, Synaptotagmin-11 Proteins
Many biological assays use antibodies to detect Synaptotagmin-11, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Synaptotagmin-11 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Synaptotagmin-11 antibodies...
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SYT11 Infographic by Boster Bio
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SYT11 Overview
Facts about Synaptotagmin-11.
Synaptotagmin-11 (SYT11)
May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. .
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Gene Information
| Human | |
|---|---|
| Gene Name: | SYT11 |
| Uniprot: | Q9BT88 |
| Entrez: | 23208 |
Family
| Belongs to: |
|---|
| synaptotagmin family |
Alternative Names
DKFZp781D015; KIAA0080synaptotagmin 12; MGC10881; MGC17226; synaptotagmin XISYT12; synaptotagmin-11; sytXI
Molecular Weight
Mass (kDA):
48.297 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1q22 |
| Sequence: | 1; NC_000001.11 (155859502..155885199) |
Subcellular Localizations
Cytoplasmic vesicle membrane; Single-pass membrane protein. Perikaryon. Golgi apparatus, trans-Golgi network membrane; Single-pass membrane protein. Recycling endosome membrane; Single-pass membrane protein. Lysosome membrane; Single-pass membrane protein. Cytoplasmic vesicle, phagosome. Cell projection, axon. Cell projection, dendrite. Cell junction, synapse, postsynaptic density. Recycling endosome membrane; Single-pass membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Single-pass membrane protein. Perikaryon. Localized in vesicles that travels in axonal and dendritic
Diseases
- Parkinson Disease
- Schizophrenia
- Diabetes Mellitus, Non-insulin-dependent
- Malnutrition
- Parkinsonism, Juvenile, Autosomal Recessive
- Juvenile Parkinson's Disease
- Attention Deficit Hyperactivity Disorder
- Tissue Adhesions
Interacting Proteins
- APPBP2
- ATP13A2
- SGTA
Pathways
- Pathogenesis
- Cell Adhesion
- Methylation
- Translation
- Insulin Secretion
- Aging
- Exocytosis
PTMs
- Methylation
Research Areas
- Neuronal Cell Markers
- Neurotransmission
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SYT11
bosterbio.com/bosterbio-gene-info-cards/SYT11
References
PMID: 12925569 by Huynh D.P., et al. The autosomal recessive juvenile Parkinson disease gene product, parkin, interacts with and ubiquitinates synaptotagmin XI.
PMID: 27278822 by Bento C.F., et al. The Parkinson's disease-associated genes ATP13A2 and SYT11 regulate autophagy via a common pathway.