Smoktcr Antibodies

AND Smoktcr ELISA kits, Smoktcr Proteins

Many biological assays use antibodies to detect Smoktcr, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Smoktcr in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Smoktcr antibodies...

We validate the specificity of these antibodies to Smoktcr by testing them on tissues known to express Smoktcr positively and negatively. Browse below to find the Smoktcr antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Smoktcr Infographic by Boster Bio

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Smoktcr Overview

Facts about Sperm motility kinase Tcr mutant form.

Smoktcr 3D structure. Source: alphafold

Sperm motility kinase Tcr mutant form (Smoktcr)

While the main function of Smoks is to control sperm motility, the function of Smok-Tcr, with reduced kinase activity, is to counterbalance a signaling handicap caused by the distorter/sterility loci, giving t-sperm an edge in reaching the oocytes. Transmission ratio distortion also called segregation distortion is the name given to the phenomenon above-mentioned.

Being connected with the T-complex, it allows males heterozygous for a complete t-haplotype to preferentially transmit the t- haplotype chromosome. .

Gene Information

Mouse
Gene Name:	Smoktcr
Uniprot:	A2KF29
Entrez:

Family

Belongs to:

protein kinase superfamily

Alternative Names

Sperm motility kinase Tcr mutant form

Molecular Weight

Mass (kDA):
54.619 kDA

Genomic Context


Mouse

Location:
Sequence:	;

Tissue Specificity

Testis-specific. Expressed in the testis from 22 days postpartum (22 dpp). Expressed late in spermiogenesis, only in Tcr-containing t-haplotypes.

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Smoktcr

References

PMID: 10647005 by Herrmann B.G., et al. A protein kinase encoded by the t complex responder gene causes non- Mendelian inheritance.