Spred2 Antibodies

AND Spred2 ELISA kits, Spred2 Proteins

Many biological assays use antibodies to detect Spred2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Spred2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Spred2 antibodies...

We validate the specificity of these antibodies to Spred2 by testing them on tissues known to express Spred2 positively and negatively. Browse below to find the Spred2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for Spred2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the SPRED2 IHC Guide

Spred2 Infographic by Boster Bio

All Spred2 Products

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Product

Figures

Specificity

Applications

Price

Anti-SPRED2 Antibody Picoband®

Western blot analysis of SPRED2 using anti-SPRED2 antibody (A06368-1)

IF analysis of SPRED2 using anti-SPRED2 antibody (A06368-1) and anti-Tubulin Alpha antibody (M03989-3)

Flow Cytometry analysis of HepG2 cells using anti-SPRED2 antibody (A06368-1)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A06368-1
100 µg/vial

SPRED2 (NM_181784) Human Over-expression Lysate

SPRED2 Human Over-expression Lysates NM_001128210

Human

$960
Cat # LS200734
20 µg, 100 µg

Anti-Spred2 Antibody

Human

ELISA, WB

$481
Cat # A06368
0.1 mg

Spred2 Overview

Facts about Sprouty-related, EVH1 domain-containing protein 2.

Sprouty-related, EVH1 domain-containing protein 2 (Spred2)

Negatively regulates Ras signaling pathways and downstream activation of MAP kinases. .

Gene Information

Mouse
Gene Name:	Spred2
Uniprot:	Q924S7
Entrez:	114716

Family

Belongs to:

No superfamily

Alternative Names

FLJ31917; MGC163164; SPRED2; Spred-2related sequence; sprouty-related, EVH1 domain containing 2; sprouty-related, EVH1 domain-containing protein 2

Molecular Weight

Mass (kDA):
46.794 kDA

Genomic Context


Mouse

Location:	11\|11 A3.1
Sequence:	11;

Tissue Specificity

Predominantly expressed in lung, liver and testis. In testis, it is specially found in mature spermatids projecting into the lumen of the seminiferous. Strongly expressed in glandular epithelia. Also expressed in embryonic tissues such as heart, lung, liver and brain.

Diseases

Malignant Neoplasms
Neoplasms
Carcinoma
Liver Carcinoma
Liver Neoplasms
Neoplasm Metastasis
Melanoma
Down Syndrome
Dwarfism
Neurofibromatosis 1
Neurofibromatoses
Hyperplasia
Drug-induced Liver Injury

Malignant Tumor Of Colon
Myeloid Leukemia, Chronic
De Novo Mutation
Injury To Liver
Tumor Angiogenesis
Myeloid Leukemia
Hemorrhage

Pathways

Cell Proliferation
Cell Motility
Secretion
Cell Migration
Localization
Rna Interference
Aging
Regulation Of Signal Transduction
Regulation Of Gene Expression
Lymphangiogenesis
Chondrocyte Differentiation
Endothelial Cell Proliferation
Flight

System Development
Cell Cycle
Bone Development
Hormone Secretion
Egg Activation
Pancreas Development
Oocyte Maturation

PTMs

Phosphorylation
Ubiquitination

Dephosphorylation
Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Spred2

References

PMID: 11493923 by Wakioka T., et al. Spred is a Sprouty-related suppressor of Ras signalling.

PMID: 15580519 by Engelhardt C.M., et al. Expression and subcellular localization of Spred proteins in mouse and human tissues.