Polyprenol reductase Antibodies

AND Srd5a3 ELISA kits, Polyprenol reductase Proteins

Many biological assays use antibodies to detect Polyprenol reductase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Polyprenol reductase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Polyprenol reductase antibodies...

We validate the specificity of these antibodies to Polyprenol reductase by testing them on tissues known to express Srd5a3 positively and negatively. Browse below to find the Srd5a3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for Polyprenol reductase? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the SRD5A3 IHC Guide

Srd5a3 Infographic by Boster Bio

All Srd5a3 Products

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Anti-SRD5A3 Antibody (C-term)

SRD5A3 Antibody (C-term) western blot analysis in 293, LNCaP, PC-3, NCI-H292 cell line lysates (35ug/lane)

Human

Flow Cytometry, IHC-P, WB

$299
Cat # A08082
80 µl

SRD5A3 (NM_024592) Human Over-expression Lysate

Human

$628
Cat # LS079644
20 µg, 100 µg

Srd5a3 Overview

Facts about Polyprenol reductase.

Polyprenol reductase (Srd5a3)

Plays a vital role in early steps of protein N-linked glycosylation by needing the conversion of polyprenol into dolichol. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation.

Referred to as a polyprenol reductase that promotes the reduction of this alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism. Also able to convert testosterone (T) into 5-alpha-dihydrotestosterone (DHT).

Gene Information

Mouse
Gene Name:	Srd5a3
Uniprot:	Q9WUP4
Entrez:	57357

Family

Belongs to:

steroid 5-alpha reductase family

Alternative Names

Polyprenol reductase

Molecular Weight

Mass (kDA):
37.936 kDA

Genomic Context


Mouse

Location:	5\|5 C3.3
Sequence:	5;

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Srd5a3

References

PMID: 11116088 by Wilsbacher L.D., et al. The mouse Clock locus: sequence and comparative analysis of 204 kb from mouse chromosome 5.

PMID: 20637498 by Cantagrel V., et al. SRD5A3 is required for converting polyprenol to dolichol and is mutated in a congenital glycosylation disorder.