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- Table of Contents
Synaptopodin-2 Antibodies
AND Synpo2 ELISA kits, Synaptopodin-2 Proteins
Many biological assays use antibodies to detect Synaptopodin-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Synaptopodin-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Synaptopodin-2 antibodies...
Designing an IHC experiment for Synaptopodin-2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the SYNPO2 IHC GuideSynpo2 Infographic by Boster Bio
All Synpo2 Products
Product
Figures
Specificity
Applications
Price
Human
$960
Cat # LS171024
20 µg, 100 µg
Cat # LS171024
20 µg, 100 µg
Synpo2 Overview
Facts about Synaptopodin-2.
Synaptopodin-2 (Synpo2)
Has an actin-binding and actin-bundling action (PubMed:11673475). Can induce the formation of F-actin networks.
In the sarcomeric Z lines is proposed to serve as adapter protein that links nascent myofibers to the sarcolemma through ZYX and may play a role in early assembly and stabilization of the Z lines. May play a role in chaperone- assisted selective autophagy (CASA) involved in Z lines maintenance in striated muscle under mechanical strain; can connect the client-processing CASA chaperone machines to a membrane- tethering and fusion complex providing autophagosome membranes.
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Synpo2 |
| Uniprot: | Q91YE8 |
| Entrez: | 118449 |
Family
| Belongs to: |
|---|
| synaptopodin family |
Alternative Names
synaptopodin-2; synaptopodin 2
Molecular Weight
Mass (kDA):
116.527 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 3|3 G1 |
| Sequence: | 3; |
Tissue Specificity
Expressed in skeletal muscle, heart, colon, stomach, uterus and lung. Expression is restricted to muscle cell layers in colon, uterus and stomach.
Diseases
- Malignant Neoplasms
- Neoplasms
- Malignant Neoplasm Of Prostate
- Prostatic Neoplasms
- Neoplasm Metastasis
- Malignant Neoplasm Of Urinary Bladder
- Cell Invasion
- Neoplasm Invasiveness
- Bladder Neoplasm
- Carcinoma
- Myopathy
- Embryonal Carcinoma
Pathways
- Localization
- Nuclear Import
- Nuclear Export
- Methylation
- Cell Migration
- Cell Motility
- Transport
- Cell Proliferation
- Neural Crest Cell Migration
- Protein Targeting
- Neuron Differentiation
PTMs
- Methylation
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Synpo2
bosterbio.com/bosterbio-gene-info-cards/Synpo2
References
PMID: 11673475 by Weins A., et al. Differentiation and stress-dependent nuclear-cytoplasmic redistribution of myopodin, a novel actin bundling protein.
PMID: 15883195 by Faul C., et al. Promotion of importin alpha-mediated nuclear import by the phosphorylation-dependent binding of cargo protein to 14-3-3.