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Tectonic-2 Antibodies

AND Tctn2 ELISA kits, Tectonic-2 Proteins

Many biological assays use antibodies to detect Tectonic-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Tectonic-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Tectonic-2 antibodies...

We validate the specificity of these antibodies to Tectonic-2 by testing them on tissues known to express Tctn2 positively and negatively. Browse below to find the Tctn2 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Tctn2 Infographic by Boster Bio

Tctn2 protein infographic

All Tctn2 Products

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Anti-Tectonic-2 TCTN2 Antibody

Western blot analysis of TCTN2 in SK-N-SH cell lysate with TCTN2 antibody at 1 μg/mL

Western blot analysis of TCTN2 in SK-N-SH cell lysate with TCTN2 antibody at 1 μg/mL

Human, Mouse

ELISA, WB

$481
Cat # A11196
0.1 mg

TCTN2 (NM_024809) Human Recombinant Protein

Coomassie blue staining of purified TCTN2 protein

Coomassie blue staining of purified TCTN2 protein

$1062
Cat # PROTQ96GX1
20 µg

Anti-TCTN2 Mouse Monoclonal Antibody [Clone ID: OTI1C1]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TCTN2 (Right lane) cDNA for 48 hrs and lysed

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TCTN2 (Right lane) cDNA for 48 hrs and lysed

HEK293T cells transfected with either TCTN2 (Myc-DDK-tagged) overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-TCTN2 antibody (M11196)

Anti-TCTN2 mouse monoclonal antibody (M11196) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY TCTN2

Human

Flow Cytometry, IF, WB

$523
Cat # M11196
100 µl

TCTN2 (NM_024809) Human Over-expression Lysate

TCTN2 Human Over-expression Lysates NM_024809

TCTN2 Human Over-expression Lysates NM_024809

Human

$628
Cat # LS079867
20 µg, 100 µg

Anti-TCTN2 Antibody

Human, Mouse, Rat

ELISA, IF, IHC, ICC, WB

$370
Cat # A11196-1
100 μl/vial

Tctn2 Overview

Facts about Tectonic-2.

Tectonic-2 (Tctn2)

Component of the tectonic-like complex, a complex localized in the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for hedgehog signaling transduction.

.

Gene Information

Mouse
Gene Name:	Tctn2
Uniprot:	Q2MV57
Entrez:	67978

Gene Information

Family

Belongs to:

tectonic family

Family

Alternative Names

C12orf38; chromosome 12 open reading frame 38; FLJ12975; TECT2tectonic 2; tectonic family member 2; tectonic-2

Molecular Weight

Mass (kDA):
77.111 kDA

Molecular Weight

Genomic Context


Mouse

Location:	5\|5 F
Sequence:	5;

Tissue Specificity

Significant expression is observed in brain, kidney and eye.

Diseases

Familial Aplasia Of The Vermis
Congenital Cerebral Hernia
Cystic Kidney Diseases
Ciliary Motility Disorders
Polycystic Kidney Diseases
Cerebellar Diseases
Eye Abnormalities
Polydactyly
Retinal Degeneration
Ataxia
Dysplasia
Congenital Hand Deformities

Multisystem Disorder
Ectopic Tissue
Bone Diseases, Developmental
Meckel-gruber Syndrome
Cleft Palate
Congenital Foot Deformity
Muscle Hypotonia

Disease

Pathways

Cell Migration
Axon Guidance

Pathways

PTMs

Glycoprotein

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Tctn2

References

PMID: 16357211 by Reiter J.F., et al. Tectonic, a novel regulator of the Hedgehog pathway required for both activation and inhibition.

PMID: 21565611 by Sang L., et al. Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.