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- Table of Contents
4 Citations 11 Q&As
5 Citations 7 Q&As
1 Citations 4 Q&As
Facts about Transforming growth factor beta-3 proprotein.
Human | |
---|---|
Gene Name: | TGFB3 |
Uniprot: | P10600 |
Entrez: | 7043 |
Belongs to: |
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TGF-beta family |
ARVD; ARVD1; FLJ16571; LDS5; RNHF; TGFB3; TGFbeta 3; TGF-beta 3; TGF-beta3; TGF-beta-3; transforming growth factor beta-3; transforming growth factor, beta 3
Mass (kDA):
47.328 kDA
Human | |
---|---|
Location: | 14q24.3 |
Sequence: | 14; NC_000014.9 (75958061..75983011, complement) |
[Latency-associated peptide]: Secreted, extracellular space, extracellular matrix.; [Transforming growth factor beta-3]: Secreted.
There are a variety of things to consider to ensure you get the best TGFB3 ELISA kit. These are the best tips to maximize your Boster Bio experiments. These suggestions can guide your experiment design to improve your results and optimize your experiments. Every researcher is likely to encounter challenges in their research. There are a variety of reasons for this and proper control can help to eliminate these issues. Troubleshooting guides can help you identify the root of the problem and help you fix them.
Boster Bio TGFB3 Boster Bio TGFB3 TGF Beta3 (CLIA ELIISA KIT) is a microwell strip plate ELISA Kit for the quantitative determination of TGF-Beta3 concentrations in biological samples. The kit uses an enzyme-linked immunosorbent test that measures TGFB3 undiluted in body fluids. It is sensitive enough to detect TGFB3 in samples containing the oligopeptides as well as peptides. It does not cross-react with other ligands.
The company produces high-quality monoclonal antibodies, antigen arrays, and other products for life sciences. The TGFB3 / TGF Beta3 (CLIA) ELISA Kit from Boster Bio has been tested for use in multiple applications, such as immunoassays, cell selection, and Flow Cytometry.
TGF beta 3 plays a significant role in the development of the lungs in mammals. It also regulates ECM formation within tissues, including skin. It plays a key role in wound healing and regulates the movement of epidermal and dermal cells that are damaged in the skin. It activates beta-catenin, Smad4 and other proteins to promote cell adhesion.
Boster Bio's TGFB3/TG beta3 (CLIA ELISA Kit) has high reproducibility. It has been tested for high sensitivity and is available in many concentrations. It is available in various formats and in multiple Reagents. It is highly recommended by researchers looking to determine the levels TGFB3 in a variety of biological materials.
Boster Bio offers an optimization guide to improve the accuracy of your Western blot or IHC analyses. These guides cover every aspect of any test, including preparation of samples, antigen retrieval, and fixing. These guides also include 150useful troubleshooting suggestions and tips to assist you in resolving common problems. You can access this information online at any time and from anywhere.
The optimization guides provide answers to the most frequently asked questions related to ELISA experiments. These guides offer information on the various types of antibodies, as well as the methods to prepare them. They also contain the best blocking buffers. They also answer the most frequently asked questions regarding ELISA results, such as how to prepare a negative control. Boster Bio's guides are available to researchers from all over the world and include ELISA optimization strategies, protocols, and troubleshooting tips.
Endothelial-mesenchymal Transition (EndMT) is caused by TGF-b signaling. This results in the growth of multipotent cells. They are essential in the development of the cardiovascular system during the embryonic stage and has been linked to the progression of cancer and fibrotic conditions. EndMT can be stimulated by the powerful transforming growth factor (TGF-b).
TGF-b proteins play a major role as a in the development of embryonic stem cell lines. They also regulate numerous cell-cell interactions during the development process. TGF-b is present in three distinct forms in mammals. The precursor proteins are alike in that they each contain a 112-amino acid polypeptide that remains in contact with a latent component of the molecule.
The involvement of TGFB3 in the development of the orofacial area has not been confirmed, however some populations have exhibited an important link. Lidral et al. The positive relationship between TGFB3 genetic and nonsyndromic oral clefts in CL/P families with central European origin was identified by Lidral et al. In another study, Morkuniene et al. found a significant correlation between TGFB3 and nonsyndromic orofacial clefts.
TGFb-3 plays an important role in the regulation and growth of cells. It also plays a role in the development of muscles in the skeletal system. This protein is created in the bone marrow. It regulates cell growth, differentiation, motility, and death. This protein plays an essential role in cancer, infectious diseases, as well as auto-immune diseases. It is worth looking into the possible applications of TGF b markers in cancer research.
PMID: 3164476 by ten Dijke P., et al. Identification of another member of the transforming growth factor type beta gene family.
PMID: 3208746 by Derynck R., et al. A new type of transforming growth factor-beta, TGF-beta 3.
*More publications can be found for each product on its corresponding product page