Them4 Antibodies

Acyl-coenzyme A thioesterase THEM4 (Them4)

Has acyl-CoA thioesterase activity towards medium and long-chain (C14 to C18) fatty acyl-CoA substrates, and likely plays a part in mitochondrial fatty acid metabolism. Plays a role in the apoptotic process, possibly via its regulation of AKT1 activity (By similarity).

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Gene Information

Mouse
Gene Name:	Them4
Uniprot:	Q3UUI3
Entrez:	75778

Family

Belongs to:
THEM4/THEM5 thioesterase family

Alternative Names

C-terminal modulator protein; CTMPCarboxyl-terminal modulator protein; MGC29636; thioesterase superfamily member 4

Molecular Weight

Mass (kDA):
26.031 kDA

Genomic Context

Mouse
Location:	3|3 F2.1
Sequence:	3;

Diseases

• Neoplasms
• Malignant Neoplasms
• Cell Transformation, Neoplastic
• Optic Atrophy
• Sclerosis
• Non-neoplastic Disorder
• Neoplasms, Experimental
• Glioma
• Hypoxia
• Carcinoma
• Dysplasia
• Fibrosis

• Cortical Dysplasia
• L1 Acute Lymphoblastic Leukemia
• Fatty Liver
• Adenocarcinoma
• Non-small Cell Lung Carcinoma
• Congenital Neurologic Anomalies

Pathways

• Localization
• Cell Death
• Pathogenesis
• Transport
• Oxygen Homeostasis
• Liver Development
• Demethylation
• Glucose Homeostasis
• Mitochondrial Fusion
• Methylation

• Sensitization
• Membrane Depolarization
• Cell Growth
• Glucose Transport

PTMs

• Phosphorylation
• Cleavage

• Methylation
• Demethylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Them4

The Best Uses of the THEM4 Marker

Troubleshooting manuals are available for the THEM4 flowcytometry kits. They provide valuable insight into optimal experimental design. They are also useful primers for new researchers and offer helpful tips and tricks to solve common problems. Boster Bio also offers flow cytometry tools that include antibodies against Methanol as well as Saponin. They can also be used to monitor intracellular signalling proteins.

Boster Bio Stanniocalcin-1 antibodies

Monoclonal as well as polyclonal antibodies can be used to detect the presence of stanniocalcin-1 when studying cancer. These antibodies can bind to a protein known as STC-1 in many animal tissue, including liver, peripheral and medulla blood leukocytes, and the adrenal medulla. Boster Bio created its Stanniocalcin-1 antibody using mice and rabbits as models. These antibodies are not detectable on human tissue (brain, liver, peripheral blood leukocytes).

NGF

The THEM4 Marker is a great tool to design for accessibility. Its versatility means that you can add accessibility to any page with no technical knowledge. You can size a marker using either its basic symbol properties or a relative position. This tool also enables you to apply offsets to translate the marker away from the feature geometry. The THEM4 marker has many great uses. Continue reading to learn more. These are just a few examples of all the possibilities.

The THEM4 markers can be used in drawing point symbols or polygons. It allows you to create markers symbols with a particular shape, and to place them relative to geometry. There are three types of symbol layers: Default, Format Symbol and Custom. The Symbology tab or the Layers Tab allow you to change the properties of the marker symbol. The default options include the first two. Select the Format Symbol mode option to change the shape of a symbol.

PLM1 as an indicator of microbial proliferation

The Boster Bio PLM1 as a Microbial Growth Indicator is a high-affinity microbial growth indicator with the ability to detect PLM1 peptides in a wide variety of samples. These antibodies are highly cited and trusted in the research community. Additionally, they have been validated for use in Western Blotting, Immunohistochemistry, and ELISA.

Diagnostic test IL6

IL-6 is an important cytokine that is rapidly induced during the course of an infection. Sepsis increases may indicate a more severe inflammatory response. This can be used as a diagnostic tool for sepsis or systemic inflammation response syndrome (SIRS).

Interleukin-6 can be produced by many cells of the body. It helps regulate the immune system's response. An individual's inflammatory response can be monitored by a blood test for IL-6. Although IL-6 is a part of a large group of cytokines it plays multiple roles in the human body, especially in the immune system. It is a "inflammatory cascade", a series of coordinated activation of immune responses.

A meta-analysis of CRC studies was conducted to determine if IL6 could be used as a diagnostic tool. The sensitivity and specificity of IL6 were determined using random-effect and fixed-effect models. To assess the effectiveness and diagnostic potential of IL-6, researchers also calculated the study-specific hazard rations (HRs). To determine if IL6 is a useful test for diagnosing cancer, we reviewed all relevant papers.

Patients with multiple conditions may have higher levels of IL6. Chronic inflammation is a common cause of aging-related diseases. People with certain diseases such as autoimmune disorders, chronic infections, Alzheimer's disease, and certain types of cancer may have elevated levels of IL-6. Although fasting for this blood test is not required, it is recommended that patients continue to take all prescribed medications.

IL6 testing is becoming more common and widely available. Their quantitative results might not be accurate because of the inconsistency among the different IL-6 reagents. The lower limit of quantitation of IL-6 was 4.0 pg/ml. However a high concentration cytokine was necessary to confirm the diagnosis.