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- Table of Contents
Talin-1 Antibodies
AND TLN1 ELISA kits, Talin-1 Proteins
Many biological assays use antibodies to detect Talin-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Talin-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Talin-1 antibodies...
Designing a Western blot for Talin-1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the TLN1 Western Blot GuideDesigning an IHC experiment for Talin-1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the TLN1 IHC GuideTLN1 Infographic by Boster Bio
All TLN1 Products
Product
Figures
Specificity
Applications
Price
Anti-Talin 1/TLN1 Antibody Picoband®
2 Citations
Human, Mouse, Rat
IHC, WB
$370
Cat # A02859-1
100 μg/vial
Cat # A02859-1
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, WB
$370
Cat # M02859
100 μg/vial
Cat # M02859
100 μg/vial
Anti-Talin 1/TLN1 Antibody Picoband®
1 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A02859-2
100 μg/vial
Cat # A02859-2
100 μg/vial
TLN1 Overview
Facts about Talin-1.
Talin-1 (TLN1)
Probably involved in connections of major cytoskeletal structures to the plasma membrane. High molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell connections (By similarity).
. .
Gene Information
| Human | |
|---|---|
| Gene Name: | TLN1 |
| Uniprot: | Q9Y490 |
| Entrez: | 7094 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
ILWEQ; KIAA1027; talin 1; Talin1; talin-1; TLN; TLN1
Molecular Weight
Mass (kDA):
269.767 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 9p13.3 |
| Sequence: | 9; NC_000009.12 (35696948..35732195, complement) |
Subcellular Localizations
Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell surface. Cell junction, focal adhesion. Colocalizes with LAYN at the membrane ruffles. Localized preferentially in focal adhesions than fibrillar adhesions (By similarity).
Diseases
- Tissue Adhesions
- Neoplasms
- Malignant Neoplasms
- Carcinoma
- Cell Invasion
- Neoplasm Metastasis
- Neoplasm Invasiveness
- Cell Transformation, Neoplastic
- Mouth Neoplasms
- Mammary Neoplasms
- Ovarian Neoplasm
- Liver Carcinoma
- Prostatic Neoplasms
Interacting Proteins
- EGFR
- ERBB2
- ITGB1
- ITGB3
Pathways
- Cell Adhesion
- Integrin Activation
- Proteolysis
- Cell Cycle
- Rna Interference
- Cell Migration
- Localization
- Cell Motility
- Cell Differentiation
- Cell Growth
- Focal Adhesion Assembly
- Secretion
- Regulation Of Binding
PTMs
- Phosphorylation
Research Areas
- Cell Biology
- Cellular Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TLN1
bosterbio.com/bosterbio-gene-info-cards/TLN1
References
PMID: 10610730 by Ben-Yosef T., et al. Characterization of the human talin (TLN) gene: genomic structure, chromosomal localization, and expression pattern.
PMID: 10320340 by Luo G., et al. Molecular interactions of N-RAP, a nebulin-related protein of striated muscle myotendon junctions and intercalated disks.
2 Publications of Boster Talin-1 Antibodies & ELISA Kits
- PubMed ID: 10.1096/fj.201801949RR, Talin promotes integrin activation accompanied by generation of tension in talin...
- PubMed ID: 32742451, Song Y,Li C,Fu Y,Xie Q,Guo J,Li G,Wu H.Inward Tension of Talin and Integrin-rela...
*More publications can be found for each product on its corresponding product page