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- Table of Contents
Talin-1 Antibodies
AND TLN1 ELISA kits, Talin-1 Proteins
Many biological assays use antibodies to detect Talin-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Talin-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Talin-1 antibodies...
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TLN1 Infographic by Boster Bio
All TLN1 Products
Product
Figures
Specificity
Applications
Price
Anti-Talin 1/TLN1 Antibody Picoband®
2 Citations 7 Q&As
Human, Mouse, Rat
IHC, WB
$370
Cat # A02859-1
100 μg/vial
Cat # A02859-1
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A02859-2
100 μg/vial
Cat # A02859-2
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, WB
$370
Cat # M02859
100 μg/vial
Cat # M02859
100 μg/vial
TLN1 Overview
Facts about Talin-1.
Talin-1 (TLN1)
Probably involved in connections of major cytoskeletal structures to the plasma membrane. High molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell connections (By similarity).
. .
Gene Information
| Human | |
|---|---|
| Gene Name: | TLN1 |
| Uniprot: | Q9Y490 |
| Entrez: | 7094 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
ILWEQ; KIAA1027; talin 1; Talin1; talin-1; TLN; TLN1
Molecular Weight
Mass (kDA):
269.767 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 9p13.3 |
| Sequence: | 9; NC_000009.12 (35696948..35732195, complement) |
Subcellular Localizations
Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell surface. Cell junction, focal adhesion. Colocalizes with LAYN at the membrane ruffles. Localized preferentially in focal adhesions than fibrillar adhesions (By similarity).
Diseases
- Tissue Adhesions
- Neoplasms
- Malignant Neoplasms
- Carcinoma
- Cell Invasion
- Neoplasm Metastasis
- Neoplasm Invasiveness
- Cell Transformation, Neoplastic
- Mouth Neoplasms
- Mammary Neoplasms
- Ovarian Neoplasm
- Liver Carcinoma
- Prostatic Neoplasms
Interacting Proteins
- EGFR
- ERBB2
- ITGB1
- ITGB3
Pathways
- Cell Adhesion
- Integrin Activation
- Proteolysis
- Cell Cycle
- Rna Interference
- Cell Migration
- Localization
- Cell Motility
- Cell Differentiation
- Cell Growth
- Focal Adhesion Assembly
- Secretion
- Regulation Of Binding
PTMs
- Phosphorylation
Research Areas
- Cell Biology
- Cellular Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TLN1
bosterbio.com/bosterbio-gene-info-cards/TLN1
References
PMID: 10610730 by Ben-Yosef T., et al. Characterization of the human talin (TLN) gene: genomic structure, chromosomal localization, and expression pattern.
PMID: 10320340 by Luo G., et al. Molecular interactions of N-RAP, a nebulin-related protein of striated muscle myotendon junctions and intercalated disks.
2 Publications of Boster Talin-1 Antibodies & ELISA Kits
- PubMed ID: 10.1096/fj.201801949RR, Talin promotes integrin activation accompanied by generation of tension in talin...
- PubMed ID: 32742451, Song Y,Li C,Fu Y,Xie Q,Guo J,Li G,Wu H.Inward Tension of Talin and Integrin-rela...
*More publications can be found for each product on its corresponding product page