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- Table of Contents
Facts about Transmembrane 4 L6 family member 5.
Human | |
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Gene Name: | TM4SF5 |
Uniprot: | O14894 |
Entrez: | 9032 |
Belongs to: |
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L6 tetraspanin family |
Transmembrane 4 L6 family member 5
Mass (kDA):
20.823 kDA
Human | |
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Location: | 17p13.2 |
Sequence: | 17; NC_000017.11 (4771886..4783211) |
Intestine. Overexpressed in pancreatic cancers.
Lysosome membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Localization to cell membrane increases during conditions of arginine depletion and translocation to lysosome membrane seen upon arginine repletion.
PMID: 9479038 by Mueller-Pillasch F., et al. Identification of a new tumour-associated antigen TM4SF5 and its expression in human cancer.
PMID: 20399237 by Kim H., et al. TM4SF5 accelerates G1/S phase progression via cytosolic p27Kip1 expression and RhoA activity.