TMCC2 Antibodies

AND TMCC2 ELISA kits, TMCC2 Proteins

Many biological assays use antibodies to detect TMCC2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TMCC2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TMCC2 antibodies...

We validate the specificity of these antibodies to TMCC2 by testing them on tissues known to express TMCC2 positively and negatively. Browse below to find the TMCC2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TMCC2 Infographic by Boster Bio

All TMCC2 Products

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Product

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Specificity

Applications

Price

TMCC2 (NM_014858) Human Over-expression Lysate

Human

$960
Cat # LS009911
20 µg, 100 µg

Anti-TMCC2 Antibody

Human, Mouse, Rat

ELISA, WB

$370
Cat # A15276-1
100 μl/vial

TMCC2 Overview

Facts about Transmembrane and coiled-coil domains protein 2.

TMCC2 3D structure. Source: alphafold

Transmembrane and coiled-coil domains protein 2 (TMCC2)

May be involved in the regulation of the proteolytic processing of the amyloid precursor protein (APP) possibly also implicating APOE. .

Gene Information

Human
Gene Name:	TMCC2
Uniprot:	O75069
Entrez:	9911

Family

Belongs to:

TEX28 family

Alternative Names

cerebral protein 11; FLJ38497; HUCEP11; hucep-11; KIAA0481; transmembrane and coiled-coil domain family 2; transmembrane and coiled-coil domains 2; transmembrane and coiled-coil domains protein 2

Molecular Weight

Mass (kDA):
77.449 kDA

Genomic Context


Human

Location:	1q32.1
Sequence:	1; NC_000001.11 (205227946..205273343)

Subcellular Localizations

Endoplasmic reticulum membrane; Multi-pass membrane protein. Concentrates in discrete patches along peripheral endoplasmic reticulum tubules.

Diseases

Anemia
Rheumatic Heart Disease
Alzheimer's Disease
Physiological Stress

Interacting Proteins

AES
APOE
CDR2
CFAP206
DPY30

EIF4E2
FAM161A
FAM90A1
HSPD1
IQUB

KAT5
PRPF31
RHOXF2
WT1-AS
ZNF417

ZNF581
ZNF587

Pathways

Enucleation
Response To Stress
Epithelial To Mesenchymal Transition

PTMs

Methylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TMCC2

References

PMID: 21593558 by Hopkins P.C., et al. The impact of a novel apolipoprotein E and amyloid-beta protein precursor-interacting protein on the production of amyloid-beta.

PMID: 24454821 by Zhang C., et al. Transmembrane and coiled-coil domain family 1 is a novel protein of the endoplasmic reticulum.