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- Table of Contents
TNFRSF6B Antibodies
AND TNFRSF6B ELISA kits, TNFRSF6B Proteins
Many biological assays use antibodies to detect TNFRSF6B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TNFRSF6B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TNFRSF6B antibodies...
Designing an IHC experiment for TNFRSF6B? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the TNFRSF6B IHC GuideTNFRSF6B Infographic by Boster Bio
All TNFRSF6B Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$499
Cat # EK0748
96 wells/kit, with removable strips.
Cat # EK0748
96 wells/kit, with removable strips.
TNFRSF6B Overview
Facts about Tumor necrosis factor receptor superfamily member 6B.
Tumor necrosis factor receptor superfamily member 6B (TNFRSF6B)
Decoy receptor that can neutralize the cytotoxic ligands TNFS14/LIGHT, TNFSF15 and TNFSF6/FASL. Protects against apoptosis.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | TNFRSF6B |
| Uniprot: | O95407 |
| Entrez: | 8771 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
DcR3; DCR3Decoy receptor for Fas ligand; Decoy receptor 3; M68; M68DJ583P15.1.1; TNFRSF6B; TR6; TR6DcR3; tumor necrosis factor receptor superfamily member 6B; tumor necrosis factor receptor superfamily, member 6b, decoy
Molecular Weight
Mass (kDA):
32.68 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 20q13.33 |
| Sequence: | 20; NC_000020.11 (63696652..63698684) |
Tissue Specificity
Detected in fetal lung, brain and liver. Detected in adult stomach, spinal cord, lymph node, trachea, spleen, colon and lung. Highly expressed in several primary tumors from colon, stomach, rectum, esophagus and in SW480 colon carcinoma cells.
Subcellular Localizations
Secreted.
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Malignant Paraganglionic Neoplasm
- Neoplasm Metastasis
- Adenocarcinoma
- Inflammation
- Autoimmune Reaction
- Rheumatoid Arthritis
- Arthritis
- Tissue Adhesions
- Autoimmune Diseases
Interacting Proteins
- KRTAP10-9
- TNFSF14
Pathways
- Pathogenesis
- Cell Proliferation
- Cell Death
- Cell Activation
- Secretion
- T Cell Activation
- Immune Response
- Cell Adhesion
- T Cell Proliferation
- Cell Cycle
- Response To Lipopolysaccharide
- Programmed Cell Death
- Inflammatory Response
PTMs
- Cleavage
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TNFRSF6B
bosterbio.com/bosterbio-gene-info-cards/TNFRSF6B
References
PMID: 9872321 by Pitti R.M., et al. Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer.
PMID: 10318773 by Yu K.-Y., et al. A newly identified member of tumor necrosis factor receptor superfamily (TR6) suppresses LIGHT-mediated apoptosis.